Reversible Cell injury Irreversible Cell injury 1. Blebbing of cell membrane 1. Breakdown of cell membrans 2. Swelling of endoplasmic-R 2. Breakdown of ER and and mitochondria. mitochondria 3. Nucleus is intact 3. Nucleus is burst Fragmented. 4. Myelin figures are 4. Myelin figures are more present prominent. 5. No amorphous densities 5. Amorphous densities are present in mitochondria are seen 6. No leakage of cellular 6. Leakage of cellular contents. (In necrosis) contents. 7. No inflammation 7.Inflammatory response is present in necrosis but absent in apoptosis