Jaundice Location Qualitative Time questions Previous questions Context at onset Ideas on what might have caused it Lifestyle changes around the time How has it been affecting your life Anything makes it worse Anything makes it better Associated features: Itch Rash Nausea Fatigue Vomit Muscle pain Weight loss Abdominal pass Urinary symptoms Abdominal distension Altered bowel habits Altered mental status Medications Prescription Non-prescription medications General history Vaccinations Screening Allergies Blood transfusions Piercings Tattoos Past medical history Ask generally GIT Surgeries Family history Social history Diet Travel alcohol Smoking Infectious contacts Recreational drug history Alcohol history Sexual history Number and gender of partners Contraceptives STIs, Differentials Acute alcoholic hepatitis Alcohol Malaise Nausea Fatigue Fever Weight loss Alcohol withdrawal symptoms: Tremor Agitation Tachycardia Alcohol withdrawal seizures Alcohol withdrawal delirium Hep A Jaundice Dark urine Anorexia Nausea Vomit Pale stools Itching RUQ pain ROUTE OF TRANSMISSION: FECAL ORAL ROUTE Hep B RUQ pain Fever Skin rash Arthritis Myalgias Anorexia Nausea Jaundice Fatigue ROUTE OF TRANSMISSION: SEX (ESP. UNPROTECTED), BLOOD AND PERINATAL (DURING CHILDBIRTH BABY MAY AQUIRE IT) Hep C Malaise Fever Myalgias Arthralgia RUQ pain Tender hepatomegaly Nausea Vomit Diarrhea Jaundice ROUTE OF TRANSMISSION: SEX (ESP. UNPROTECTED), BLOOD AND PERINATAL (DURING CHILDBIRTH BABY MAY AQUIRE IT) Hep D Similar to hep B ROUTE OF TRANSMISSION: SEX (ESP. UNPROTECTED), BLOOD AND PERINATAL (DURING CHILDBIRTH BABY MAY AQUIRE IT) Hep E Similar to hep A ROUTE OF TRANSMISSION: FECAL ORAL ROUTE Cholangitis Abdominal pain High fever Jaundice Reynolds pentad -> Charcot (fever, jaundice and high WBC) triad plus HoTN and mental status changes. Infectious mononucleosis Splenomegaly Fever Fatigue Malaise Pharyngitis Tonsilitis Hepatomegaly Maculopapular rash Jaundice Cirrhosis Itch Jaundice Caput medusae Palmar erythema Nail clubbing Petechiae Purpura