**Fibromyalgia** **Clinical Features:** * Widespread pain in 11 of 18 tender points * Sleep disturbances - fatigue, morning stiffness * Difficulty concentrating, memory problems, "Fibro Fog" * Headaches * Irritable Bowel Syndrome * Anxiety/Depression * Muscle aches * Numbness/tingling * Bladder problems * Raynaud's phenomenon **Associated Symptoms:** * Fatigue * Sleep disturbances * Cognitive difficulties (fibro fog) * Headaches * Irritable bowel syndrome * Anxiety/depression * Muscle aches * Numbness/tingling * Bladder problems * Raynaud's phenomenon **Pathophysiology:** * Central Sensitization - increased sensitivity of pain pathways in the brain and spinal cord. * Altered pain processing - the brain becomes more sensitive to pain signals. * Dysfunction of the autonomic nervous system. * Neurotransmitter imbalances. * Genetic predisposition. **Diagnosis:** * Widespread pain index (WPI) score of ≥ 7 * Symptom severity scale (SSS) score ≥ 5 * Pain must be present for at least 3 months * Pain in at least 11 of 18 tender points * No underlying medical condition to explain the pain **Treatment:** * **Non-pharmacological:** * Education and support * Regular exercise * Stress management techniques * Cognitive behavioral therapy * Physical therapy * Occupational therapy * **Pharmacological:** * Pain relievers (e.g., acetaminophen, ibuprofen, naproxen) * Antidepressants (e.g., duloxetine, milnacipran) * Anticonvulsants (e.g., gabapentin, pregabalin) * Muscle relaxants (e.g., cyclobenzaprine) * Sleep aids (e.g., melatonin, trazodone)