University:
Camosun College
Course:
BIOL 252 | Pathophysiology for Nursing 1
Academic year:

2024
Views:

188

Pages:

3
Author:

Aysha A.

# Hemachinamatosis Hemochromatosis is defined accumulation of body ivon AS the excessive Hemachiamato sis chromatosis cdisonder mag to be 10/ heriditara homo other acosired or genetic hemochromatosic disorder due to - Homozygous excessive vecessive ithevitad absaphon of ivon Martations of gener encoding HFE Hereditary homachiomaiosis 11" hemochromatosis / Hemasiderasis of inn secondong to - Acconciation other disorders in tissues ↑001ntake of inom chronic Liver disease B thalassemia, sideroblastic anemia parental ivan overlead sickle call disease, oplastic anemia Hemodialysis Plequired overload > pathoapnesis Mertations HJV, TFR 2. HFE gener cutich leads to absance of Hepcidin → ever when there is Leads to absorption of Fe scostantial elevation of body stoves Leads to mainly the cake is 209 liver accomodation of iven e samptami appears mae stored ins aben Laboratory findings Raised som ivon, 4% sotcration, nor binding capacita ↑ serem femitin, Mechanism of tisscie damage Damages sapthesis of hadvokal fhee radicals Free radica famation peroxidation damages issue ba pipid 2 Activation collage of hepatic stellate pamation cells stimalardes 3 Interaction of reactive avith DNP results predisparition to xagan spazier & of man lethal cell hepatocellular carcinoma (flation of iron of fe fonction cells are reversible Herapa promotes recovery avith remoxa of tissce organs Liver, pancreas, mopcardiom pituitary gland, adrenal joints El skin. gland, thaieid, present aith cirrhosis ہے pancreatic fibrosis Marphokag Cirrhosis of Liver de to mchorodolar cintiosis chocolate broan Hemochromatosis lator becoma colour → Initialla moaronadalav deposists Pigmont fiest appear as artoplasm the frelep giantar cell00 A Easila recognised dae aulth prussian blue stain starr them clinical manifestations Excessive Move accord아아 usaalla acpected → sbau a Preglessive price develops dering sth to oth decade in males classical triad : Miatonaddar amhasie Diabetes Mellitas skin pigmentation in all patients. →bronze diabetes Death moa resealt for hepatocelidar comicinoma. canhosis cardiac discover Amebic Liver Doease Major complication of intestinal anebiasis E. histoleptica trophozortes pom the Liver through partal circalation. cdan may och trophozoites kill hepatocarter→ podace abcess Pbcess semisolid paste in cavita is filled with dark boon, odoorless necrotic material clock El ashich vesendes onchas consistenca spread of amebic Liver abcess spread capsule of Liver 4 mag expona ana rupture thiocat → moi directly spead into peritoneam, diaphragm, pleural cavity, lungs pericardiam or Hermatogenous spead to the brain & kidney necrotic lesions dinical featover of ameable Liver abcess severe opper quadront pain, loou grade ferver, aeight loss, Diagnosis is made by radiobge antrascend donanst of docess conjunction with serelogical testing for antibodies E histolertica