University:
Camosun College
Course:
BIOL 252 | Pathophysiology for Nursing 1
Academic year:

2024
Views:

38

Pages:

3
Author:

Aysha A.

ENDOCRINE PHARMACOLOGY YOUVA D ORAL ANTE DIABETIC DRUMS sulfonyl ureas:: tgen Tolbutamide 2nd gen: glibeclamide ②Biguanide, Metformen Meglitinide analoques, Repaglonide 4) I phenyl alanine der: Nateglinide Thiazolidine drones Praglitazone -Glucosidase inhibitor: Acarbose, Meglital 3) Rapeptidyl peptidase-y: - Stagigton - CDPPH whiziton) - Saxagliptin 8)SULT-2 inhibitors : Dapaglifuzon. Csodium glucose transporter -2) Suffinyl creare band to specific receptor on fcells ofislatig ↓ Pancreas MOA Block ATP-sensitive potasium channel ↓ Depolartration & influx of cart nito scell. Degranulation and release of stored anrubn from Buell hr sulphonyl areas, atteast 20% hunctional Bells pecessary. sulphonyl urease increase no fonsulin receptors. Page YOUVA ③ reduce the release of glucagon. A/E: Hypoglycaemia, cuith glibenclamide & Chlorpropamcide Ge distrubances: Naurea, vomiting, drallhuea ③ weight gom. Allergic reaction skin rashes, stching & photosensitivity Teratogenicity not safe during pregnancy- 1 Insulen analogues: prduced DNA recombinant technology AA seg slightly different 2types FoustHamot saw & tong Acting Rapid Neting Baseden Bichon mod. eq: ensulin lispo Thr. Reale affect. Insulin aspart 15mh Insulin Glulisine Action Actionet shurt acting Tusulan Regular soluble Insulen Intermediate acting insulin NPH (Esuphanequsulon) long acting insulen Dinsulen Detemer 2) Rusulin Glargine 2) Corticosteroids YOUVA MOA of Insulen Insulen bend to Tyrosine kinone recaptors 2 subunits 22 26 T entra cellulas Frummensbreme proteon ↑ Bond to with tyrosine lomase Tativity Romsters entry of glutase tor vations Cols of the body Iusenbon - Gets phosphorylated - Action is Inhibit glycogendyses & gluconergenices. ⅱ) bnhiet lopolyses (i) Enhances entry gamino acid into muscle call & cells. patern dynther's (N) Peripheral utilization of glucose and Ikt