University:
Camosun College
Course:
BIOL 252 | Pathophysiology for Nursing 1
Academic year:

2024
Views:

146

Pages:

3
Author:

Aysha A.

19) classify Auto epilecter drugs?. Phenytoin. MOA - clinical use Epilepsy AlB Convulsions - disorder of brain funct. Paroxysmal Cerebral Lysarrytthimia * CLASSIFICATION: HI Balu Chandra Shekhar Cycled from Brahma Putra Hydatorn: Phenytoin 2). Imano stilbenes, Carbamazepine 3) Barbiturates Phenobarbitone 4) Carboxylic acid derivative : Sodium valproate 5) Succinimide Ethosuximide •6) Cyclic GABA Bralogues: Pregabalin, Gabapentin 7) BZD's: Lorazepam, diazepam. •8) Phenyl tragine: Lamotrigine MOA of anti epileptic drugs on Nat Channels: Phenytorn Band to Voltage gated Nat channel (Rawing mactive Hate and prevent huither entry of Natxons into neulon. (stabilife neuronal membrane) ↓ Inhibit generation of repetitive Action put. Suppreis high freq firing newtons Prevent freduce Spread of Seifure discharges. B20, Barbiturate, GABA A LABA Act. GABA B2D kaulitate GADA Pathway! Sodium Valpnate GABA Actircity) Pheno Fac. GABA AEF CGRBA-T Pramotes WABA release Vågabatrim barbitune Blocksuptake of GABA auto neulons Ice Conductance into the neulon -Tragabine Hyperpolarrsation Reduced neuronal excitability Anti paleptre effeat Voltage day. Nam els channels - Restery state - Activated state gnactivated state Reduces intra neulonal Nat Concentration. Cmembrane Stabilering effect Inhibit the generation repetitive action potentiad Phenytoon bands to voltage gated Nat channels (prolongest the nactivated state) Prevent husther entry Nat qute the neulon PREE Prevent reduce spread ofserfure discharges Inhibit the high frequency firing wes' @GTCS Corrand mal epilepsy) @Pattial seizures ③ Trigeminal and other neuralgias. status epilepticus Lo seifure seifire that lasts more than 5 mim nure than I seifure in 5min. A/E: (H'S) Hypertrophy & Hyperplasia of gums (due to defect on Collorgen Catabdiom) Hypersensitivity reactions skin rashes, neutropenia Hirsutism - ↑ Andigen secretion {excesstre hair growth } Hyperglycemia- - I ansellin release Megaloblastic anaemia - Folate deficiency osteomalacia - ↑ metaboliem of vit D. Hypocalcemia- I absorption of Calcium in the gut. BZD - Controlling status epilepticus"