University:
Camosun College
Course:
BIOL 252 | Pathophysiology for Nursing 1
Academic year:

2024
Views:

74

Pages:

3
Author:

Aysha A.

Benfodiazepine antagonist (flumagénil) Competitively inhibits effect of both B2D antagonist Cons depression) + BZD antagonist ('CNS stimulation) High First peun metabolism • Fluma Zenil used on treatment of BZD overdasage. reverse sedative effect of BZD. • Can also be used for reverse the hypnotic effect of Nun BZD'S Zolpidem, zaleplon, eczopidone. Non BZD - Zalpidam • & anti aziaty - Zaleplon I anti convulsant - Zopiclone anti muscle relaxant eczopiclone less than BZD less potential for abuse than BZD. Flumazenl - can be used to treat overdose. Zolpidem - hypnotic effect I sleep latency↑ dulation of sleeptime Causes morimal hangerer & rebound insomnia lacks anti convulsant, cuts anriety, and muscle relaxant effects cuell absorbed, metabulized on lever, and excreted in urine Common side effects: headache, confusion, hausee & Vomiting. MOA Zolpidem, Zopiclone, Zaleplon, eczoplinone Bend selectively to B20 binding to GABA, receptor Faciliated ↓ GABA mediated neuronal Inhibition. CNS depresston. (B2D) Diazepam permotype drug) oral 5-10mg, iv, rectal - V - Rapidly absorbed an as traut - Prod. Sitive metabulite - used to control convulsions but not for long term theraphy of epilepty L ↳ rapid development of tolerance to anticonculs ant effect. -Lan be used rectall rectally to cintral Convulsions. Classification of sedative & Hypnotics B2D Barbituratzi Non B2D Diazepam Lorazepam midazalan Long Acting: Phenobarbitone. Zolpidem short Acting, Pento bal bitone Zulpicine ultra shurtacting: Thiopentine Zaliplom • metro heartone exzapidone melatonin ramelteon