University:
Camosun College
Course:
BIOL 252 | Pathophysiology for Nursing 1
Academic year:

2024
Views:

172

Pages:

3
Author:

Aysha A.

ormation Drugs affecting Coagulation & Blood of Anti Coagulants invitro Hepalon. • Judium Citrate Parenteral crat bidium cxalate Indirect thrombon direct altepatin (unfractiuned hep) •linw. mol weight Hepaton • Brvalirudon Argatroban •Synthetic: Fondapaxinux Coumarin derivat. Deveet thromben warfarion • documeral • Dabigatran 0 Doreet Radar Xa inhibiter •Rivaroxaban. trimar fystem Brührensic system Vila Prittivamen →Thremben (lla) →leren (soluble) VIII A Horan (stable) Low mole culad merght heparin MTWTFE Page fin Date YOUVA Enurapalin LMWHIS Ebtained hom hactionation of Heparin datteparin Finzap arin reviparin SUBCUTANEOUS' Produce Anticoagulant effect by Inactivation of factor Xa - by anti thrombon unlike Hepalon Is dues not have sufficient length can bond to thromben f auto thrombon Hence very lithe affect on Thramben (a) aPTT munitoring nit required. {Patients with chronic renal faiture Factor xa excreted through Kidney effect LMW It's not completely reverseamone by "Protamine hulphate" Page Advantages Date: YOUVA @highes Bioavailability (2) higher T½ adm. aday once a ③ does not require APTT monitorony low chance of after perosis A/E: 30 HH BOA → Reversible Mipecian. hypersensit →usterporosis Bleeding hepum Heparon induced thrombocytopenia, formaten of antibodies against platelet foctor - heparin Complex ↓ platelet Crunt Th highes UFH than LMWIH'S. hypersensstrelly reactions. skin rashes, lever, urticaria. Bleeding man side effect serious hatal hemmorhage. uromary IGIT APTT muntarong needed on UFA on lik threatening hemorrhage sww V Protamone hulphate Cheparon antagonist