University:
Camosun College
Course:
BIOL 252 | Pathophysiology for Nursing 1
Academic year:

2024
Views:

215

Pages:

2
Author:

Aysha A.

7/6/22 Acid-Base Homeostasis-: Alkalosis 1-111203 1 Metabulic dou to deficit in excess ↓ lass of HEO of HLOS Clinical investigations- Arterial blood gas analysis -1pH, Pey 2 Hсоз somple used Arterial blood (Not renous) Mason venous Good is much variable →Normal pH-7-35 40 743 POOL 35-45mm Hg Heo 22-26 mmol/L Anion gap 15±5 mmol/L Anion gap Difference to measured anions & calisons is 1525 m Signilicanu For differential diagnosis with acid-base disord Melabolic acidosis ↑organic acid / loss of HCO3 ↓ excretion of ↓ H+ Causes - kutoacidolis (Type 1 diabetes) Diarrhea renal failure Lactic acidosis renal tubular acidosi's → methanol poisoniy → Salicylic acich poisoning. Biochemical changes- →PHY, HO, Ploz ٠ resep compensation : reep rath 1, yper ventilation → Hyperkalemia (serum (+1) Renal compensation! - H+ is excretid synthesis of NH3 Reabsorption of HCO3 Respiratory acidosis (excess H₂CO₃) cause Disorder of lung causing hypoventitalion. eg. Asthma, Honchitis, emphysema, pneumonia etc Depression of Resp entre ag: Anaesthitia, sedalin. Biochemical changes- - No resp compensation → H+ overeted, Heaz-eablorbed ↑ synthesis of Nuz. Metabolic Alkalosis (↑↑ HCO3-) Causes Loss of Htion (vomiling, gantric aspirationg →Alkal irgestion Biochemical fineling- F-T Resp comp Hyperenitation Resp Alkalosis(2). causes Meningitis salicylic poisoning, wrebral trauma -hypoxia Biochemical finding → PH↑, соз, но - No resp compensation Lanal compensation Hypokal ma excretiel, ↓ reabsooption Hсоз- HC