University:
Coventry University
Course:
B940 | Biomedical Science
Academic year:

2024
Views:

404

Pages:

5
Author:

Badusha S

Factors affecting wound healing Local factors: 1. Infection. It causes persistent tissue injury and inflammation. 2. Mukanical factors- Movement of wounded area may compressant the blood vessels and separate the edges of the wond and 3. Foreign -Ha foreign boodies os even bone can delay heally! bodies:- 4. Size & kype of wound - small surgical incisional, another inj heal quickly with less scar formation than large excisional wounds or wounds caused by blunt trauma. Is the location of injury hours over the skin covering the be 6 Blood supply wounds in areas with good wood supple Such a dace, heal faster than those with your blood supply, such as the foot. ionizing 7. Radiation uses a repair process. 8 complications may deby wound thed healing. Systemic factors: 1. Nutritional deficiencies: such as protein deficiency, vit (deficiency, copper & Zinc deficiency. 2 wound healing is Age:- individuals. rapid young compared to aged Diabetes Mellitus delays wound healing. 14. Inadequate blood supply delays wound healing. 5 Hormones:- Glucocorticoids have anti-inflammatory eddess, thereby ingrair word healing." 6 Defects in neutrophils slows may slow healing process. complications of wound healing I adequate Granulation tissue formation: It can cause wound dehiscence & ulceration. 1. Dehiscence: as supture of a wound is mod common life- threatening complication atter abdominal surgery. 2. Ulceration wounds can ukesate due to inadequate angiogenesis during healing. s.lucisional hernia!- resulting from weak seers of the abdominal wall due to a defect caused by prior surgery. Excessive Sean Sormation: Excessive formation of the components of the repair process. Can result in; 1. Hypertrophic der The accumulation of excessive amounty of of extracellular matrix, mostly collages may give rise a raised scar at the site of wound. 2. ttoiokaloid the scar tissue grows/progresses beyond the boundaries of the orginal wand and does not regress. 3. Gruberent geamulation:- (a) pyogenic granuloma. Excessive Contraction: A Jise in the size of a wound dus to myofibroblasts is known as Contractikas. An exaggeration of this contraction is termed on Contracture. Consequences of contractures; 1. Compromise movements:- for example, contractures that Ellow severe bums can compromise Ame movement of the invalid region and joint movements.