University:
Eastern Kentucky University
Course:
BIO 315 | Genetics
Academic year:

2022
Views:

428

Pages:

2
Author:

Nesbyenvkk

Chapter 7: Sex Chromosome and Mitochondrial Inheritance and Disorders ____ 1. Which feature is common among people who have Klinefelter syndrome (47,XXY) or a karyotype ____ 2. Which single physical feature is most often associated with a 47,XXX karyotype? D. Height greater than siblings ____ 3. What is the risk for a man with a 47,XYY karyotype to produce a child with a 47,XYY karyotype? B. 50% ____ 4. Why is the incidence of an extra Y chromosome in the general population unknown? A. The phenotype is that of a normal male. ____ 5. A male patient is tall and has some gynecomastia along with a low sperm count. During infertility ____ 6. Which health screening activity is most important for girls and women with Turner syndrome? C. Blood pressure screening ____ 7. What is the most likely mechanism for a 45,X karyotype? B. Nondisjunction ____ 8. Which of the following definitions accurately represents the concept of expansion? with 47,XXX but not among people who have Down syndrome or Edward syndrome? C. Tall stature testing, he was found to have a 47,XXY karyotype. Which disorder is consistent with these findings? C. Klinefelter syndrome B. The number of trinucleotide repeat sequences within the noncoding region of a specific gene allele is increased. ____ 9. What is the function of the FMR1 gene? A. Promoting brain development and maintaining neuronal synapses ____ 10. At what specific location on an X chromosome is a break most likely to occur in fragile X syndrome? C. End of the q arm ____ 11. Which of the following mechanisms in fragile X syndrome (FXS) leads to expression of the disorder? B. Trinucleotide repeat sequences causing methylation of the FMR1 gene, thus silencing its expression ____ 12. Which condition or health problem is more common in women who have an FMR1 mutation? D. Menopause before age 40 years ____ 13. What would be the expected consequence to two daughter cells after mitosis if the ability to produce mitochondria was lost? C. The rate and amount of ATP production would be limited. ____ 14. Which clinical feature in a newborn baby girl suggests the possibility of Turner syndrome? B. Presence of a webbed neck ____ 15. Which trait or characteristic in a 10-year-old-girl would lead her pediatrician to consider the possibility of androgen insensitivity syndrome? B. She is color-blind, and her father is not. ____ 16. Which type of problem results from mutations in mitochondrial DNA (mtDNA)? A. Reduced cellular energy ____ 17. What factor most strongly influences the development of the paramesonephric tissue into female sex organs? D. The absence of a Y chromosome ____ 18. Which process can cause a person with an XY genotype to have a female phenotype? D. Failure of gene expression resulting in a complete absence of androgen receptors ____ 19. On which chromosome is the androgen receptor (AR) gene located? C. X ____ 20. A man and his sister are both affected with a mitochondrial disorder. Because the sister has two children who also have the disorder, the man is concerned about the possibility of also having children with the disorder. What is the estimated risk for each pregnancy of this man producing a child with the same mitochondrial disorder that he has if his wife does not have a mitochondrial disorder? D 0%