GPAT 2020 - Drugs Inspector Questions and Answers

2020 1. Violin gut is obtained from intestine of: A. Camel B. Sheep (Ans} C. Horse D. Cat 2. As per European Pharmacopoeia technical guide, substance stored at 25° C for 24 hours at 80% RH, called very hygroscopic when increase in weight is: A. 2'.: 0.2% w/w and < 15% w/w B. � 0.2% w/w and < 2% w/w C. 2'.: 15% w/w (Ans} D. � 0.2% w/w and < 20% w/w 3. Dimethyl sulfoxide acts as penetration enhancer for topical formulations by : A. Increasing transepidermal Joss B. Altering solvent nature of membrane C. Denaturing proteins (Ans) D. !increasing solubility 4. An excipient Ludipress used for liquid Dosage form is a coprocessed excipient of: A. B. C. D. Dextrose monohydrate + Kollidon 30 Lactose monobydrate + Kollidon 30 Dextrose monohydrate + Kollidon 30 + Kollidon CL Lactose monobydrate + Kollidon 30 + Kollidon CL (Ans) 5. Relative sweetness of sucrose, to saccharin : A. I : 500 (Ans) B. I : 200 C. 1: 100 D. 1: 400 6. SCHICK Test Toxin is a sterile Filtrate from a culture of: A. Actinobacillus mallei B. Mycobacterium Dipbtberiae C. Rickettsia prowazek:i D. CorynebacteriumDiphtheriae Ans 7. Type II glass containers are: A. B. C. D. Most inert glasses and shows high hydrolytic resistance Suitable for most acidic and neutral aqueous preparations (Ans} Suitable for alkaline solutions Suitable for non-aqueous preparations 8. Lakes of Dyes available commercially contain maximum upto ___ of pure dye. A. 50% (Ans B. 15% C. 25% D. 10% 9. Pyrogen present in containers can be destroyed by heating the containers at : C. 121°C for l5mins D. 210°C for 4 hr (Ans) A. 121 °C for 30 mins B. 2J0°C for 1 hr l 0. In capsule making the Bloom strength of gelatin is proportional to molecular weight of the gelatin and is a measure of the: A. B. C. D. Adhesive strenght of gelatin with dipping pins Adhesive strength of gelatin with other polymer Cohesive strenght of the crosslinking that occurs between gelatin molecules (Ans) Cohesive strength of solvent molecules J 1. FoJlowing statement is more accurate with respect ot limitations of Arrhenius relationship for stabil.ity prediction : A. Equal moisture concentrations will be mentioned at different temperatures B. Order of degradation will alter at higher temperatue C. Same degradation mechanisms may predominate at different temperatures D. Less relative humidity and oxygen solubility at higher temperature (Ans) J 2. The second law of thermodynamics states that 'whenever a spontaneous process ta.Ices place, it is accompanied by an increase in the total energy of the uoivers' The equation that satisfies the above law is : A.�Suniverse = Ssurrounding - �Ssystem = Ssystem + �Ssurrounding (Ans) B. �Suniverse C. �Ssystem = Sumverse D.�Suniverse = Ssystem + �Ssurrounding - �Ssurrounding J 3. Method of Study Dmg Distribution pattern is A. Flourimetry B. UV-visible spectrophotometry C. Nuclear magnetic resonance D. Mass spectrophotometry (Ans) 14. The Acidic polymers of Ribitol / Glycerol phosphate present in Gram positive microorganism are known as : A. Peptidoglycans B. Polysacchaiides C. Lysozymes D. Teichoic acids (Ans) 16. In the process of Extration, ethanol is used as a solvent for : A. Alkaloids (Ans) B. Sucrose C. Waxes D. Gum 15. According to distribution law, select the appropriate expression for the concentration of a soJute when it exist as monomer in solvent A and dimer in solvent B. CA= concentration of solute in solvent A, Cn = concentration of solute in solvent B, a= degree of dissociation. CA A. K= 2x {cff CA m B. K = -- (Ans) CA C . K=----CB ( 2- a) CA D. K=----- CB(1-a) 17. While studying solid state physicocbemical properties, lhe packing property of drug include: A. Entropy B. Heat capacity C. Solubility D. Refractive index (Ans 18. Centistoke is tibe CGS unit for the following property : A. Surface tension B. Coefficient of viscosity C. Fluidity D. Kinematic viscosity (Ans) 19. The dispersion of course material by shearing in a narrow gap between a static cone and a rapidly rotating cone is caused by A. Electrical Dispersion B. Colloid mills (Ans) C. Peptisation D. Ultrasonic Irradiation 20. Molar heat capacity of a system is defined as : A. The amount of heat required to raise temperature of one mole of the system by one Kelvin. (Ans) B. The amount of beat required to decrease temperature of 1 mole of the system by 1 Fahrenheit C. The amount of heat required to raise temperature of one mole of the system by one Fahrenheit D. The amount of heat required to decrease temperature of one mole of the system by one Kelvin. 21. Which of U1e following is not a fundamental (primary) factor considered for selection of a location for the construction of pharmaceutical or chemical plant ? A. Market for products B. Raw materials C. Soil (Ans) D. Labor supply 22. Which of the following powder shows the greatest degree of dustibility? A. Potato Starch B. Talcum powder C. Fine charcoal D. Lycopodium powder (Ans) 23. Human Serum Albumin has a molecular weight of: A. 59,000 B. 34,000 C. 44,000 D. 65,000 (Ans) 24. Which of the fol1owing is the example of "Invert Sugar"? A. Sucralose B. Lactulose C. Lactose D. Sucrose (Ans) 25. Production of Acetyl methyl carbinol can be detected by which of the following test? A. Voges-proskaver test (Ans) B. Methyl red test C. Citrate utilization test D. Indole test 26. Increasing tile proportion of disperse phase of an emulsion by more than 60% may lead to: A. Phase inversion (Ans) B. Frothing C. Creaming D. Cracking 27. The unequal attractive forces acting on tile molecules at the surface of Hquid gas interface when compared witil molecular forces in tile bulk of tile liquid is due to: A. B. C. D. Absence of adhesive force of attraction Less cohesive force of attraction Absence of cohesive force of attraction Less adhesive force of attraction (Ans) 28. When six suppositores containing 20% of morphine HCI in Theobroma oil are to be prepared, which of the following statement is correct ? (Given: Displacement value of morphine HCl is 1 .5; weight of each suppository is Jg) A. B. C. D. The displacement values of both morphine HCI and tileobroma oil are to be considered The displacement value of morphine HCJ is to be ignored (Ans) The displacement value of Theobroma oil is to be considered The displacement value of morphine HCl is to be considered 29. The polymorphs exhibit the following different properties except: A. Chemical structures (Ans) B. Melting points C. X-ray crystal & diffraction patterns D. Solubilites 30. Following amino acid does not exhibit optical isomerism: A. Glycine (Ans) B. Serine C. Leucine D. AJanine 31. Riboflavin, Chemically is A. 6,7-dimethyl isoalloxazine (Ans) B. 8,9-dimethyl isoalloxazine C. 8,9-diethyl isoalloxazine D. 6,7-diethyl isoalloxazine 32. Fraction of administered dose (which may be in form of an ester of salt) of active drug is termed as: A. Formulation factor B. Salt factor (Ans) C. Intrinsic factor D. Activity factor 33. The 'Crenulation' effect on the cell wall is caused by __ solutions and this effect is__ A. Hypertonic; reversible (Ans) B. Hpotonic; reversible C. Hypertonic; irreversible D. Hypotonic; irreversible 34. If two monosaccharides differ in their structure around a single carbon atom, they are called as___ A. Trimers B. Epimers (Ans) C. Dimers D. Trioses 35. The following gram positive bacteria species is positive for the coagulase test ( a test for the ability of bacteria to cause blood plasma to clot). A. S. aureus (Ans) B. S. saprophyticus C. S. epidem1idis D. S. /actis 36. The complexation of Quinine with hexyl salicylate is an example of absorption by: A. Penocytosis B. Ion pair transport (Ans) C. Convective transport D. Facilitated transport 37. The drug concentration between Minimum effective concentration (MEC) and maximum safe concentration (MSC) is called: A. Therapeutic range (Ans) B. Therapeutic index C. Therapeutic ratio D. Toxic range 38. The temperature dependence and the theory of viscosity is expressed by the following: A. Gibb's equation B. Stern-volmer equation C. An·henius equation Ans D. Higuchi equation 39. When a solid forms a gel more readily when gently shaken or otherwise sheared than when allowed to form the gel while the materia1 is kept at rest, the phenomenon is known as: A. Thixotropy B. Rheopexy (Ans) C. Antithixotropy D. Negative rheopexy 40. Drug products that contain the same therapeutic moiety but as different sa1ts, esters or complexes are called as: A. Therapeutic alternatives B. Pharmaceutical alternatives (Ans) C. Pharmaceutical equiva1ents D. Therapeutic equivalents 41. Burrow's solution is: A. B. C. D. Aluminium acetate solution strong (Ans) Calcium phosphate solution strong Ammonium acetate solution strong Calcium hydroxide solution strong 42. When the concentration of an aqueous sodium chloride solution has the same colligative properties as the solution in question, the va1ue so obtained is known as : A. Molality B. Molarity C. Isotonicity value (Ans) D. Normality 43. The version of GMP in India that describe requirement of factory premises for manufacture of cosmetics A. Schedule M-Il (Ans) B. Schedule M-III C. Schedule M D. Schedule M-1 44. When adhesive attractions between molecules of different species exceeds cohesive attraction between like molecules, the deviation according to RauJt's law is said to be: A. Partial B. Positive C. Neutral D. Negative (Ans) 45. Which of the following will result in very closest value to the Glomerular Filteration Rate? A. Albumin Clearance B. Measure of Blood Urea Nitrogen C. Creatinine Clearance (Ans) D. Insulin clearance 46. Fungus is also known as opportunistic pathogen, often isolated from warm-blooded animals A. Penicillinium ch.rysogenum B. Aspergillus niger C. Penicillinum notatum D. Candida a1bicans (Ans) 47. Following is tlie important sterol in faeces foaned from cholesterol by bacteria in lower iostestine: Note (Biomarker for presence of human faecal matter in environment) A. Coprostanol (Ans) B. 7-a-Hydroxy cholesterol C. 7-Dehydrocbolesterol D. Lithocholic acid 48. Product of the foUowing reaction : 8 B. 0 (A.n.s cyclopen�e) 49. Choose the wrong statement from the following with regard to Amorphous solids: A. B. C. D. They tend to flow when subjected to sufficient pressure They do not have definite melting point Usually they are anisotropic (Ans) Considered as super cooled fluids 50. Antifungal agent 5-fluorocytosine is converted to its active metabolite 5-fluorouracil by one of the following fungal enzyme: A. Cytosine deacetylase B. Cytosine deaminase (Ans) C. Cytosine reductase D. Cytosine demtbylase 51. What is the approximate chemical shift ranges for protons attached to aldehydic groups ? A. 6 - 7.9 o B. 9.5 - IO o (Ans) C. 1.5 - 3.5 o D. 4-8 o 53. d-tubecurarin produces skeletal muscle relaxation by inhibiting A. B. C. D. Ganglionic nicotinic receptors a-adrenergic receptors muscarinic receptors nicotinic receptors in neuromuscular junction (Ans) 52. Which of the following are physiological effects of ganglionic stimulating agents ? A. Stimulation of sympathetic ganglia and the adrenal medulla leading to CVS responses B. Initial transient stimulation & then a more persistent depression of all autonomic ganglia C. Marked depression of CNS leading to analgesia. D. Chronic exposure causes a marked increase in the density of micotinic receptors contributing tolerance and dependence. E. Combined activation of parasymapthetic ganglia and cholinergic nerve ending by nicotine results in increased tone and motor activity of the bowel. F. Inhibition of salivary and bronchial secretions that is followed by stimulation. l. A;C&D 2. A; B&D (Ans) 3. B;D&F 4. B; C&E 54. Meloxicam belongs to which class of Nonsteroidal Anti-inflammatroy Drugs (NSAIDs)? A. Selective cox-2 inhibitor B. Selective cox-1 inhibitor C. Preferential cox-] inhibitor D. Preferential cox-2 inhibitor (Ans) 55. Which of the following is not one of the triade effects of a adrenaline leading to rise in BP? A. An increased heart rate (positive chronotropic action) B. Vasoconstrktion in many vascular bed specially in precapilJary resistance vessels of skin C. Stimulation of presynaptic a-2 adrenoreceptor leading to increase sympathetic tone (Ans) D. A direct myocardial stimulation that increases the strenght of ventricular contraction. 56. Which one of the following is not the property of osmotic diurectics ? A. B. C. D. Freely filtered at the glomerulus They inhibit carbonic anhydrase (Ans) Undergo limited reabsorption by the renal tubule Are relatively inert pharmacologically 57. This 4-arnino ,quinoline atimalarial drug marketed as R, S isomer, has itwo trifluromethyl moieties at position 2 and 8 and no electronegative substituent either at 6 or 7 positions is : A. Chloroquine B. Amodiaquine C. Mefloquine (Ans) D. Primaquine 58. Which of the following is Antiaromatic ? A. Q 0 (Ans) C. D. B. 59. An aldopentose can be converted into aldohexose by: A. Kiliani-Fischer synthesis (Ans) B. Wahl's method 0 Q C. Ruff's degradation method D. Hoffmann degradation method 60. The specific reagents used in skraup synthesis of quinoline are : A. B. C. D. Benzaldehyde, Acetal of arninoethanal and Nitrobenzene Glycerol, aniline, sulfuric acid and Nitrobenzene (Ans) Beozaldehyde, aniline, sulfuric acid and nitrobenzene Glycerol, Acetal of arninoethanal and Nitrobenzene 61. One of the following statement with respect to carbachol is NOT correct Identify: A. B. C. D. It can be administered orally The amino group decreases electrophilicity of the carbonyl group It is more susceptible to hydrolysis as compared to acetylcholine (Ans) It possess both muscarinic and nicotinic action 62. Propanone and 2-hydroxy propene are: A. Tautomers (Ans) B. Rotamers C. Chain isomers D. Position isomers 63. Ion trapping is an important process in drug distribution with potential therapeutic benefit. It is defined as: A. An acidic ,drug will accumulate on the more basic side of the membrane and a basic drug on more basic side. B. An acidic drug will accumulate on the more acidic side of the membrane and a basic drug on more basic side. C. An acidic ,drug will accumulate on the more basic side of the membrane and a basic drug on more acidic side, (Ans) D. An acidic drug will accumulate on the more acidic side of the membrane and a basic drug on more acidic side. 64. The condesation of an active methylene compound with formaldehyde and an amine to fonn P-amino carbonyl compound is known as : A. Mannich reaction (Ans) B. Knoevenagel condensation C. Beckmann rearrangement D. Stobbe condensation 65. Mitomycin C is an antibiotic isolated from A. Streptomyces caespfrosus (Ans) B. Streptomyces antibioticus Streptornyces verricillus D. Streptomyces peaucelius C. 66. Hydrated proton is called A. Roxonium ion B. Proton pump C. Hydronium ion (Ans) D. Water proton 67. The principle of liquid-liquid extraction is ___ A. Partition (Ans) B. Solubility C. Separation D. Adsorption 68. Two pore domain K-+ ions channels are opened by which one of the following categories of anaesthetics ? A. Halogenated inhalation anaesthetic B. Opioid analgesics C. Barbiturates D. Benzodiazepines 69. Globar source in infra red spectrophotometer is___ A. Nichrome wire B. Tungsten filament C. Rhodium wire heated in ceramic D. Silicon carbide rod (Ans) 70. Walden inversion or compJete reversal of stereochemistry occurs in one of the fo!Jowing substitution reaction : A. SNi reaction B. SNAr reaction C. SN I reaction D. SN2 reaction (Ans) 71. What is the product of the following reaction? Ans. Q )J� c · 72. Which of the following rearrangement involves migration of a group from carbon to electron deficient nitrogen ? A. Baeyer villiger rearrangement B. Wilgerodt rearrangement C. Beckmann rearrangement (Ans) D. Pinacol-pinacolome rearrangement 73. Electron releasing groups stabilizes free radicals by A. Negative mesomeric (-m) effect B. Positive mesomeric (+m) effect C. Negative inductive (-I) effect D. Positive inductive (+I) effect (Aas) 74. Cotrimoxazole is combination of trimetboprim with suJfametboxazole. Which of the following statement is correct about cotrimoxazole? A. B. C. D. Cotrimoxazole is ineffective in treating respiratory tract infections. Most effectve ratio of trimetboprim : suJfamethoxazole in plasma is 20: J Cotrimoxazole is contraindicated during pregnancy. (Ans) T : S are administered in a dose ration of 5:1 to achieve optimal synergistic effect. 75. Which of the following drugs possesses Antiplatelet effecrts? A. Erythropoietin B. Clopidogrel (Ans) C. Desmopressin D. Urokinase 76. The principle of gas-liquid chromatography is: A. Affinity chromatography B. Partition chromatography (Ans) C. Ion exchange chromatography D. Adsorption chromatography 77. The mechanism of antiepileptic effect of Lamotrigine is by: A. Inhibition of glutamate release B. Blockade of NMDA receptors C. lnhlbition of ca++ channels D. Inhibition of Na+ channels (Ans) 78. The mechanism by which fluorides innhlbit dental caries is A. B. C. D. Increased acid solubility of enemel By increasing the sinsitivity of toooth enamel By increasing susceptibility to acid Decreased acid solubility of enamel (Ans) 79. The Nitration of quinoline gives a mixture of ___ A. 5-nitro and 8-nitroquinolines (Ans) B. 3-nitro and 6-nitroquinolines C. 2-nitro and 7-nitroquinolines D. 2-nitro and 4-nitroquinolines 80. The weakly acidic nature of warfarin is attributed to the presence of: A. B. C. D. Methylene protons on substitution at 3rd position Proton on chiral carbon Proton on hydroxyl group at 4th position Ans) Aromatic protons of coumarin cing 81. Which of ilie following groups stabilizes carobocation m elect:ropbilic aromatic substitution? A. -N(CH3)3+ , -NO2 B. -COOH, -CHO C. -NH2, -OH (Ans) D. -CN, -SO3H 82. The beterocyclic nucleus present in nitrofurantoin are: A. B. C. D. 2-nitrofuran and imidazole 2,4-ruone (Ans) 3-nitrofuran and imidazoJe 2,4-dione 2-nitrofuran and imidazoline-2-one Furan and pyrrole 83. Which on is NOT an opioid receptor? A. Delta B. Gamma (Ans) C. Mu D. Kappa 84. Closeness of a measured value to the true or accepted value is known as___ A. Precision B. Accuracy (Ans) C. Deviation D. Bias 85. The solvent used in NMR spectroscopy with the highest level of deuteriation among these is: A. Deuterum oxide B. Deuteriomethanol C. Deuterioacetone (Ans) D. Deuteriochlorofonn 86. When an electton with charge 1.60 x 10-19 coulombs is moved through a potential difference of 1 volt. the energy expended or released is called as ____ A. I Coulomb B. I Erg C. 1 eVolt (Ans) D. 1 Joule 87. identify the diuretic which causes hyperuricaemia, tend to raise serum calcium and also causes magnesium depletion ? A. Furosemide B. Acetazolamide C. Chlortbiazide (Ans) D. Mannitol 88. Which one of the following is not the biochemical marker of all death ? A. Lipase B. Pbospholipase (Ans) C. Amylase D. Creatine kinase 89. one of the followins is not a chemical or histochemical change that occurs in infarction of heart: A. Decrease in sodium (Ans) B. Glycogen depletion C. Influx of calcium D. Increse in lactic acid 90. A typical long bone consists of following parts except : A. The epiphyses B. The trabeculae (Ans) C. The periosteum D. The diaphhysis 9 J. In one of the following situations metabolic acidosis does not occw· : A. B. C. D. Chronic renal failure Production of less amount of lactic acid (Ans) Uncontrolled diabetes mellitus Therapeutic administration of acetazolamide 92. wlticb one of the following is a organ specific (localised) autoimmune dlisease? A. Scleroderma B. Rheumatoid arthritis C. Polyarteritis nodosa D. Grave's disease (Ans) 93. Rosacea is a skin condition that affect: A. Adults b/w the age of 30-60 (Ans) B. Oldage people C. Only woman D. Teenage people 94. Which of the fol1owing neurotransmitter is formed on demand and act immediately? A. Adrenaline B. Histamine C. Nitric oxide (NO) (Ans) D. Acetylcholine 95. Following pairs represent antibiotic and its source. Identify the correct pair: A. Macrolides : Actinomycetes (Ans) B. Griseofulvin : Bacteria C. Colistin : Fungi D. Polyenes: Fungi 96. In the transplant rejection the clinical features of graft-versus-host reaction includes folJowing exceptA. Fever, weight loss B. Intestinal malabsorption C. Dermititis, diarrhoea D. Rheumatoid arthritis (Ans) 97. Which one of the following statement is true for cancer cells? A. B. C. D. Cancer cells require stimulation by growth factors Oncoproteins produced by cancer cellls act an neighboring cells They produce oncoproteins in the absence of growth factors or external stimuli (Ans) Cancer cells are highly sensitive to growth inhibitory signals 98. Except one of the following pairs respresent drugs used in the treatment of glaucoma and their primary mechanism. Select the wrong pair from the followiing A. B. C. D. Topical carbonic anhydrase inhibitors : Decrease aqueous fonnation Topical miotics: Increase aqueous outflow Topical beita-adrenergic blockers: Decrease aqueous outflow (Ans) Topical prostaglandin analogues : Increase aqueous outflow 99. In Aloe the mucilage containing parencbymatous cells are present in: A. Centralparenchymatous region Ans B. Pericyclic cells C. Vascular bundles D. Epidermis 100. As per the definition of D & C Act, Gudakhu rubbed against human teeth is considered as A. Sweeting gum B. Cosmetic (Ans) C. Drug D. Food l 01. Which one of the following is not a renal osteodystropby (type of bone disease associated with chronic kidney disease)? A. Adynamic bone disease C. Osteomalacia D. Mixed renal osteodystrophy B. Secondary hypoparathyroidism (Ans) 102. Who was the Chairman of Drugs Enquiry Committee which was established in the year 1927? A. Joseph Bhore B. S.S. Bhatia C. B. Mukherjee D. RN. Chopra (Ans) 103. In yam, the presence of irregular arrangement of the fibres, the ends of which often project from the surface is because of : A. Absence of li:nters B. Absence of combing (Ans) C. Presence of impurities D. Improper drying 104. Standards to be complied under D & C act -1940 for drugs imported, manufactured, stocked and exhibited for sale or distribution are covered under : A. First Schedule B. ScheduJe M C. Second Schedule (Ans) D. Schedule L 105. The major property of Ayurvedic herbs, "Rasa" indicates A. Post digestve effect B. Physicochemical properties C. Taste (Ans) D. Potency 106. Autorhythmicity is present in which of the following group of tissues ? A. B. C. D. Cardiac muscle and visceral smooth muscle (Ans) Skeletal muscle and cardiac muscle Cardiac muscle and neuronal tissue SkeletaJ muscle and visceral smooth muscle 107. Plants which are not differentiated into root, stem and leaves are : A. Bromeliales B. Plant aginales C. Thallophyte (Ans) D. Principes 108. As per the Drugs and Cosmetics Act 1940 if a drug is not labelled in prescribed mam1er it is A. Misbranded drug (Ans) B. Substandard drug C. Spurious drug D. Adulterated drug 109. Identify phase of clinicaJ trial having following features 1. 2. 3. 4. Trial is conducted on about 3000 patients Purpose of triaJ is therapeutic confirmation Safety and tolerability is evaluated on wider scale Completion of triaJ is followed by New Drug Application (NDA) A. Phase - IV C. Phase - II B. Phase - III (Ans) D. Phase -I 110. In which year India sighned General Agreement on Trade and Tariffs (GATT) including Trade Related Intellectual Property Rights (TRIPS)? A. 1992 B. 1990 C. 1994 (Ans) D. 1996 111. Dragendorff' s reagent is : A. Potassium mercuric iodide B. Potassium picrate C. Potassium iodate D. Potassium bismuth iodide (Ans) 112. In colour test for alkaloids coJchicine with mineral acids gives : A. Yellow colour (Ans) B. Red colour C. Blue colour D. Violet colour 113. The Crystal fonn of Sulphacetamide is A. Monoclinic B. Triclinic C. Rhombohedral D. Orthorhombic (Ans) 114. In solid-solid mixing, large scale continuous type of mixer is : A. Ribbon blender B. Zigzag blender (Ans) C. Twin shell blender D. Sigma blender 115. Mechanical digestion in mouth in which food is mixed with saliva is__ and the movement of food from mouth into the stomach is ___ A. Segmentation; masticatioon B. Masticatiolll; deglutition (Ans) C. Deglutition; propulsion D. Segmentation; propulsion 116. Identify antiarrythrnic drug that increases duration of QT wave and decreases the sinus rate, whereas it bas no effect on QRS complex A. Amidarone (Ans) B. Lidocaine C. Quinidfoe D. Verapamil 117. The general sodalime glass is not a suitable material for fabricating the container for: A. Oral solutious B. Dry powders C. Liquids for external use D. Parenterals (Ans) 118. In Shikimic acid pathway, chorjsmate mutase converts chorismic acid to : A. Carotenoids B. Gutta C. Phytol D. Prephenate (Prepbenic acid) (Ans) 119. Which of the following microorganism is used for the effective synthesis of interferon? A. Pseudomonas Aureginosa B. Bacillus Subtilus C. Saccharomyces Cerevisiae (Ans) D. Micrococcus Luteus 120. The fundamental principle "Law of Similia" falls under which therapy'? A. Ayurveda B. Aroma therapy C. Homoeopathy (Ans) D. Siddba A ISO9001 B. ISO9002 (Ans) C. ISO9000 D. ISO9004 122. A fixed oiJ when added to an equal volume of ethanol clear liquid is obtained; on cooling at 00 C and on storage for three hours, the liquid remains clear such fixed oil is identified as A Soyabean oil B. Neem oil C. Castor oil (Ans) D. Evening primrose oil 123. Which one of the foUowing is not affected in respiratory tuberculosis? A Mediastinal lymph nodes B. Larynx C. Pericardium (Ans) D. Pleural cavity 124. During the denaturation cycle in polymerase chain reaction the temperature is raised to A 80-88°C B. 60-68°C C. 70-78°C D. 90-98°C