Cell Cycle, Mitisis and Meosis Part E

PART E: Multiple Choice: Select the BEST answer for the questions below. 1) If cells in the process of dividing are subjected to colchicine, a drug that interferes with the functioning of the spindle apparatus, at which stage will mitosis be arrested? A) prophase B) anaphase C) interphase D) telophase E) metaphase 2) A cell containing 92 chromatids at metaphase of mitosis would, at its completion, produce two nuclei containing how many chromosomes? A)16 B) 46 C) 12 D) 92 E) 23 3) All of the following occur during mitosis except A) the synthesis of DNA. B) the condensing of chromosomes. C) the disappearance of the nucleolus. D) the uncoupling of chromatids at the centromere. E) the formation of a spindle. 4) If a cell has 8 chromosomes at metaphase of mitosis, how many chromosomes will it have during anaphase? A)4 B) 1 C) 16 D)2 E)8 5) How do the daughter cells at the end of mitosis and cytokinesis compare with their parent cell when it was in G1 of the cell cycle? A) The daughter cells have the same number of chromosomes and the same amount of DNA. B) The daughter cells have half the amount of cytoplasm and half the amount of DNA. C) The daughter cells have the same number of chromosomes and twice the amount of DNA. D) The daughter cells have half the number of chromosomes and half the amount of DNA. E) The daughter cells have the same number of chromosomes and half the amount of DNA. 6) Movement of the chromosomes during anaphase would be most affected by a drug that A) prevented shortening of microtubules. B) increased cyclin concentrations. C) prevented attachment of the microtubules to the kinetochore. D) reduced cyclin concentrations. E) prevented elongation of microtubules. 7) Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle was the nucleus with 6 picograms of DNA? A)S B) M C)G1 D) Go E) G2 following questions consist of five phrases or sentences related to the control of cell division. For each one, select the term from below is most closely related to it. Each term may be used once, more than once, or not at all. A. PDGF B. MPF C. protein kinase D. cyclin E. Cdk 8) released by platelets in the vicinity of an injury 9) enzymes that activate or inactivate other proteins by phosphorylating them 10) fibroblasts have receptors for this substance on their plasma membranes 15 "A" answer 15 11) a protein synthesized through the cell cycle that associates with a kinase to form active enzymes 12) triggers the cell's passage past the G2 checkpoint into mitosis The questions below consist of five phrases or sentences concerned with the cell cycle. For each phrase or sentence, select the answer letter from below that is most closely related to it. Each answer may be used once, more than once, or not at all. A. Go B. G1 C. S D. G2 E. M 13) The "restriction point occurs here. 14) Nerve and muscle cells are in this phase. 15) the shortest part of the cell cycle 16) DNA is replicated at this time of the cell cycle. 17) Cyclin is destroyed toward the end of this phase. 18) What are enzymes called that control the activities of other proteins by phosphorylating them? A) kinases B) chromatin C) D) ATPases E) cyclins 19) What triggers the separation of chromatids during mitosis? A) internal signals originating at the centromere B) the activation of proteins holding sister chromatids together C) activation of an anaphase-promoting complex (APC) D) the release of platelet-derived growth factor from the Golgi E) the buildup of cyclin near the kinetochores 20) Which of the following is true concerning cancer cells? A) They have escaped from cell cycle controls. B) When they stop dividing they do so at random points in the cell cycle. C) They do not exhibit density-dependent inhibition when growing in culture. D) B and Care true. E) A, B, and Care true. 21) If the liver cells of an animal have 24 chromosomes, its sperm cells would have how many chromosomes? A)12 B) 6 C) 24 D) 48 22) What is a karyotype? A) the genotype of an individual B) the phenotype of an individual C) a display of homologous chromosomes of a cell organized in relation to their number, size, and type D) a system of classifying cell nuclei E) a unique combination of chromosomes found in a gamete 23) Eukaryotic sexual life cycles show tremendous variation. Of the following elements, which do all sexual life cycles have in common? 1. alternation of generations II. meiosis III. fertilization IV. gametes V. spores A)1, IV, and V B) II, III, and IV C) I, II, and IV D) II, IV, and V E) all of the above 24) Which of these statements is false? A) In humans, each of the 22 maternal autosomes has a homologous paternal chromosome. B) At sexual maturity, ovaries and testes produce diploid gametes by meiosis. C) In humans, the 23rd pair, the sex chromosomes, determines whether the person is female (XX) or male (XY). D) Sexual life cycles differ in the timing of meiosis in relation to fertilization. E) Single, haploid (n) sets of chromosomes in ovum and sperm unite during fertilization, forming a diploid (2n) single-celled zygote.