University:
Northwest College
Course:
VN 210 | Introduction to Pharmacology
Academic year:

2023
Views:

201

Pages:

2
Author:

Yesenia M.

amiadarone (pacerone) Potassum Channel Blocker. therapeutic class Class Il antidysrhythmic umiadorane-Sounds like aldacione Pharmacolocal dass: Potassium channel blocker. also works potassiu actions/uses: tx of resistant venticular tachycardia and preferred tx of atrial dysrhythmias in Pts CHF (kt always. It) -blocks Potassium ion channels and some Nat Channels Favailas oral tabs/ lv (IV is short term 2-Adays Potassium channel blocker pulmonary toxicity. ) uses PNA-like syndrome *requires 10-9 ram loading duse to achiere steady concentration in blood, doses are ↑ in first 2-3 weeks. Effects can last 4-8 weeks after dic blk it has exrended half life (50t days) Potassium Channel blocker -Therapeutic senmn lvl 15 0.8-2.8mcg/mL Pregnancy CATD -correct kt and ng prior to initiating med (bk can cause dysrhythmias) pregnancy CAT:D * onset: 2-3 DAYS Po peak: 3-7HKS Duration: 10-50 days 2HRS IV ale: most senous all is pulm toxicity. Coin cause liver enzymes thyroid disfunction, blue-gray skin discolaration, blurred vision, rashes, photosensitivity, nlv, anorexia, fatigue, dizziness, & BTD." prolonged half life-gle slow to resolve Black BOX VWARNING ONLY FOR ORAL FORM Causes PINA-like syndrome in lungs. (may be falal baseline (periodic assesments -Prodysrhythmic action may cause bradycardia, card Logenic of lungs neded. Shock, or Av block. -mild liver injury. Contraindications: pts I severe bradycardia) cardiogenic shock, Sick Sinus syndrome, Severe sinus, node dysfunction, 3radegree Av block. Interactions can block metabolism of warfarin give Vidose of warfarin) I beta adrenergic antagonists or CCB's may worsen sinus brady, sinus arrest Or Ar block. labs ↑ Al ALT, AST, ALP,TISH JA ANA, A Herbal/Food: I St. Johns wort reffectiveness Grapefruit juice may ↑ toxicity of amiodarmy Tx overdose: tx of amiodarone overdose is targeted on reversing hypotension I vasopressors, and bradycardia tatropine or iso proterenol