Gemfibrozil Course Materials

University:
Northwest College
Course:
VN 210 | Introduction to Pharmacology
Academic year:

2023
Views:

240

Pages:

2
Author:

Yesenia M.

gemfibrozil (genenc) - Fibric acid drugs' (stones) (LOPId) (trade/brand) Therapeutic class Antihyperlipidemic Pharmacological class: Fibric acid drug-FIBRate actions luses: for tx of hypertriglyceridemia Ca triglicerides - SEVERELY HIGH) - and hypercholesteremia (1 CHOL.) *50% reduction of VLDL + ↑ In HDL. MOA-Unknown (veffective @ -activate enzyme lipoprotem lipase, which break of triglecunde vich particles felimiukalion route: Po I meals (↓ Glupet) duse: 400-1200mg/day Onset: 1-2 hrs peak 1-2hrs duration-2-4months Pregnancy cat: B Sle: Girelated-dyspepsia/diarrhea /n/v/abd pain ale:↑ likelihood gallstones affect liver function. contraindications.in hepatic impairment pts thepo Cko, gallbladder disease, allergy Inyeysasith to drug Interactions: Can↑ anticoagulant effects when taken anticoagulant. -↑thabdomyopathy if given I statins. **effects of diabetic cirugs, Statins, insulin. LaBS: liver chzymes (glucose) creatinine phosphokinase (CPK) glucose Can HGB, HCT, WBC "Foods: Fatty food vefficacy Tx for overdose. genfibril gallstones ↑ gluwse a coagulant effects