University:
Swansea University
Course:
PM-139 | Human Physiology 1
Academic year:

2023
Views:

69

Pages:

3
Author:

Amal J.

Environmentalfactor1Lattitudecausativefactortalisearly symptomAntibodyAntibody againstAntigenForis formedMul scelerosisMultipleCHCAJsulesociimmunity isAuto inmuneImmunepresentdiseaseSystem isActivatedDemyelinationpathology:-plague is present inCerebrum, cerebellam, sp. cordecrantial nerves [Bnd, 3rd & 6th]Earlyolder lesionNO inflammationinflammationGray &Myeleh dis integrateShrchken of& fragmentsearly inflammalpart J,sheathAxonalNO mye WheethsparringAxon cylinder isperivascularless in numberinfiltrationAcellular &demarkedOedema &lesioncellular1,proliferationAffect/ delaythe nerveDemyelihation &conductiondestructionvelocityof & tructuresconduc fion isaffected.Pathology:-Antigen to produce M.SCSFBloodPerivascularplaque formationplaquein cerebrum, sp.cord& care bellumFocal neurologicalsym ptemremyelenationscelerotic plaqueRecove fromsymptomsigns & symptomsmpletlyRelapsing &progressed.re coverrecovery HIGELEDH) sensory - 40%Neth 2) Mot or - 12%3) Retrobulbar neuritis - 17%4) Diplopia - 11%5) Ataxia,20%verligosphenies7precisesensory :-1)ParasthesiaNumbnessimpaired of joint position 8vibration [Any lesion inposterior columnJ2) Dysasthesia [spiro-thalamic lesiontractwith hot or cold [withburning type sensationCentra - Lateral pain, temperatureis loss )3) thermitte's signSudden flexion ofXneck will cause shock(Buining sensation throughoutbody / limbs