University:
West Coast University
Course:
PHAR 840 | Immunologic Conditions and Special Populations
Academic year:

2024
Views:

396

Pages:

4
Author:

Asal A.

I Cost Minimization Analysis (CMA) Definition, advantages and disadvantages of CMA Rascati (Chapter 4) 1 Cost-minimization analysis (CMA) • Costs are measured in Dollars ($$) • Outcomes are assumed to be the same (or equivalent) between the two or more alternatives (or drugs) being compared ―Outcomes are not directly measured but assumed the same based on evidence from other studies 3 Examples of cost-minimization analysis (CMA) 1. Comparison of cost-effectiveness of drugs that are bioequivalent ―Effectiveness is assumed the same; however, costs may differ (thus only costs are compared) →Generic drug by Company A vs. generic equivalent by Company B (e.g., generic amlodipine by Mylan Pharmaceuticals vs. generic amlodipine by Vintage Pharmaceuticals) →Brand drug by Company A vs. generic equivalent by Company B (e.g., Norvasc® by Pfizer and generic amlodipine by Mylan Pharmaceuticals) →Brand drug by Company A vs. Brand drug by Company B containing the same active ingredient (e.g., Zestril® by AstraZeneca and Prinivil® by Merck—both contain lisinopril) 2. Measuring the cost of receiving the same medication in different health care settings ―Costs of receiving IV antibiotics in a hospital vs. home health care service →Cost of drug is the same but cost of setting where drug is received will differ 5 Arguments for and against CMA • Should it be called a cost analysis (partial PE analysis) and not a True PE analysis? ―Some argued that CMA is a partial PE analysis since only costs are measured and outcomes are not measured ―However, if outcomes were indeed measured but found to be equivalent, CMA should be referred to as CEA JIM or new drugs being brought to the market are • Not many interventions evaluated by this method ―CMA has limited use because it can only compare alternatives that have similar outcomes →Publications that use CMA are less common than other types of PE analyses 6