Enteric Fever-Clinical Features and Epidemiology

University:
Swansea University
Course:
PM134 | Microbiology
Academic year:

2023
Views:

256

Pages:

4
Author:

Yasin N.

CLINICAL FEATURES Incubation Perlod: 7-14 days (Can vary from 3-54 days depending on the dose) Relapse are common STEP LADDER PYREXIA - Fever gradually rises with every spike and then falls down ROSE SPOTS—These are hyperemic rashes that fade on applying pressure. They appear 5-7 days after infection and are usually seen in the abdomen first. They are visible properly in fair-skinned people. Early Intestinal manifestation: Abdominal pain, nausea, vomiting, anorexia, constipation leading to diarrhea or vice versa Important signs: Soft palpable Spleen, Hepatomegaly and relative bradycardia. Tachycardia is usually associated with high fevers. Ps. Complications: GI Bleeding and Intestinal perforation (due to ulceration) can occurs 3rd-4th week of illness Cholecystitis, arthritis, osteomyelitis Neurological complications: Psychosis, Deafness and Meningitis [Muttering Delirium / coma vigil) EPIDEMIOLOGY: Enteric is Endemic in India and other developing countries. Can be epidemic in a community due to common water supply or sewage as in hostels Infection Typhi: Paratyphi is 4:1 Affects all age group, more common among young age group of rural areas TYPES OF CARRIERS Note: Most often source of infection a) Convalescent Carriers - Can act as carrier upto 3 months b) Temporary Carriers - From 3 months to fyr c) Chronic Carriers - For more than a year Common in Women and old age - Biliary tract abnormalities Abnormality of urinary tract infections Fecal vs Urinary carrier In Fecal carriers typhoid bacilli multiply in gallbladder and excreted in feces; it's more common In Urinary carriers multiplication takes place in kidney and excreted in urine, urinary carriers are rare Mary Mallon Also known as Typhoid Mary, she was a cook in New York who also sadly was an chronic carrier for the disease It's reported that nearly 1300 cases of typhoid fever were caused by her!

Related Documents

Recommended Documents

Details Report

Helpful?

Description

Related Documents

Struggling with your assignment and deadlines?

Free up your schedule!

Take 5 seconds to unlock