University:
Central Michigan University
Course:
BIO 545 | Molecular Genetics
Academic year:

2023
Views:

54

Pages:

3
Author:

Nesbyenvkk

The Þgure shows four protein motifs that are involved in DNA binding. Label each Þgure with the name of the motif being shown. Glucocorticoid hormones activate genes that are involved in which of the following processes? Glucocorticoids are __________ hormones secreted by __________ glands. Arrange the following in the proper order in which they occur during glucocorticoid hormone action. a. Binding of hormone to receptor b. Release of HSP90 proteins c. Entry of hormone into the nucleus Glucocorticoid response elements function as enhancers. The glucocorticoid receptor is active as a dimer. Which of the following proteins does NOT directly interact with TFIID? A transcriptional repressor that controls the transcription of gene A is not normally active unless bound by an eﬀector molecule X. In a certain cell, the domain of the repressor that binds X is mutated so that X can no longer be bound. With all other factors being the same, what eﬀect do you predict on the transcription of gene A if X is aded to the cell when it is already transcribing gene A? A transcriptional repressor that controls the transcription of gene A is not normally active unless bound by an eﬀector molecule X. In a certain cell, the domain of the repressor that binds to the silencer of gene A is mutated so that the repressor-X complex can no longer bind to its recognition site. With all other factors being the same, what eﬀect do you predict on the transcription of gene A if X is increased in the cell and the cell is already expressing gene A? A segment of DNA that serves as a boundary that blocks the eﬀects of transcriptional regulation of one gene on another is called a/an __________. If a drug was developed that could inhibit TFIID binding to the core promoter, what would its eﬀect on transcription be? Variant histones are very prevalent in eukaryotes. The Barr body, the inactive X in eukaryotic females, is associated with which variant histone? Place the labels in the appropriate category. Labels may be used more than once. Chromatin remodeling can result in a variety of changes to chromatin structure. The Þgure depicts three of these changes. Label the pictures to indicate the type of remodeling that is taking place. Nucleosome-free regions (NFRs) are found in many eukaryotic genes. Select the statement that is NOT true about NFRs. Histone modiÞcations that occur in diﬀerent patterns that are thought to control transcription are collectively known as __________. Acetylation of histones may result in __________. DNA methylation in eukaryotes, which is associated with transcription inhibition, occurs on A residues at GATC sites. For a methylation pattern to be inherited it must __________. Which of the following were strategies that were used in the ENCODE project? Check all that apply. What would be the consequence if an individual was homozygous for an IRP allele that could not bind iron but could bind to the IRE? Possible iron toxicity to the cells at levels of iron that would not normally be toxic to a cell

Molecular Genetics Chapter 15 Homework

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