University:
Liberty University
Course:
BIOM 500 | Introduction to Biomedical Sciences
Academic year:

2024
Views:

178

Pages:

5
Author:

Sheha A.

Cori's Cycle Cori cycle is a metabolic pathway in which lactate produced by anaerobic glycolysis in skeletal muscle is converted into glucose, which can then be used by the muscle for energy. Some of this lactate is transported to the liver and is converted to glucose via gluconeogenesis. Steps: Glycolysis in Muscle: Glucose is converted to pyruvate, which is then converted to lactate. Some of this lactate is transported to the liver and is converted to glucose via gluconeogenesis. Gluconeogenesis Lactate produced in muscle is transported to liver and converted to glucose. This glucose is released into the bloodstream and transported back to muscle for energy. Steps: Lactate to Pyruvate: Lactate is oxidized to pyruvate. Pyruvate to Phosphoenolpyruvate: Pyruvate is converted to phosphoenolpyruvate in a two-step process involving carboxylation and phosphorylation.