Ketone Bodies or Acetone Bodies | Lecture Note - Edubirdie

University:
Liberty University
Course:
BIOM 500 | Introduction to Biomedical Sciences
Academic year:

2024
Views:

393

Pages:

5
Author:

Sheha A.

Ketone Bodies/Acetone Bodies These are ketone bodies present: Acetoacetate Acetone β-hydroxybutyrate Ketone Bodies Ketone bodies are water-soluble and easily transportable. β-hydroxybutyrate in that case plays an important role. Acetone cannot be metabolized further. It is a volatile organic compound. Normal serum level: 1 mg/dl Normal amount excreted: 10 mg/day Significance of Ketone Bodies: Ketone bodies being water-soluble are easily transported from the liver to various tissues. Acetoacetate and β-hydroxybutyrate serve as important sources of energy for peripheral tissues such as heart, skeletal muscle, etc. The production of ketone bodies and their utilization become significant during starvation and diabetes mellitus. During starvation, ketone bodies serve as a major fuel source for the brain and other parts of the central nervous system.

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