Amino Acid Metabolism and Disorders | Liberty University

University:
Liberty University
Course:
BIOM 500 | Introduction to Biomedical Sciences
Academic year:

2024
Views:

5

Pages:

5
Author:

Sheha A.

**Biological important compounds synthesized from various amino acids** **Amino Acid** | **Specialized Products** ---|--- Glycine | Creatine, Glutathione, heme, purines, taurine, bile acids Tyrosine | Thyroxine, triiodothyronine, epinephrine, norepinephrine, dopamine, melanin Tryptophan | NAD+, NADP+, serotonin, melatonin, niacin, epinephrine, polyamines, active methionine, histamine, epinephrine, polyamines Methionine | Active methionine, cysteine, epinephrine, polyamines Cysteine | Cysteine **Inborn errors of aromatic amino acid metabolism:** **Aromatic amino acids are:** * Tryptophan (Trp) * Phenylalanine (Phe) * Tyrosine (Tyr) **Tryptophan Disorders** * Hartnup disease * Defective intestinal absorption **Phenylalanine & Tyrosine Disorders** * Metabolic defect * Phenylketonuria * Tyrosinemia type I * Neonatal tyrosinemia **Phenylketonuria** * Phenylalanine hydroxylase **Tyrosinemia type I** * Tyrosine transaminase **Neonatal tyrosinemia** * p-hydroxyphenylpyruvate oxidase