University:
Liberty University
Course:
BIOM 500 | Introduction to Biomedical Sciences
Academic year:

2024
Views:

457

Pages:

5
Author:

Sheha A.

Digestion of Cholesterol, Esters, and Phospholipids Bile-containing solution also contains cholesterol esterase and phospholipase A2 1) Cholesterol Esterase Hydrolyzes cholesterol esters to cholesterol and fatty acids. 2) Phospholipase A2 Hydrolyzes phospholipids to lysophospholipids and fatty acids. Fatty Acids (short, medium and long chain) 2-monoglycerides Diglycerides Glycerol Lysophospholipids Phospholipids Absorption of Lipids The end products of lipid digestion, that is glycerol and monoglycerides, fatty acids are absorbed from the intestinal lumen into the portal vein and taken to the liver and incorporated into chylomicrons for excess. Certain molecules like 2-monoglycerides, long chain fatty acids, small amounts of 1-monoglycerides, cholesterol, phospholipids and lysophospholipids are incorporated into bile salt micelles. micelles and absorbed into the intestinal cells In intestinal mucosal cells, triglycerides are resynthesized and incorporated with cholesterol into chylomicrons along with other lipids and phospholipids and released into the intestine to lymphatic vessels.