University:
Liberty University
Course:
BIOM 500 | Introduction to Biomedical Sciences
Academic year:

2024
Views:

451

Pages:

5
Author:

Sheha A.

Synthesis of bile acids. Sife! Giver The step catalyzed by 72-hydroxylase is Inhibited by bik. acids and this is the rate Cemiting reaction cholic acid and chino deon primary bile acids Top Section: Taurocholic acid and glycocholic acid (derivatives of cholic acid) and taurochenodeoxycholic acid and glycochenodeoxycholic acid (derivatives of chenodeoxycholic acid) are the major bile salts. In the intestine, a portion of primary bile acids undergoes deconjugation and dehydroxylation to form secondary bile acids. These reactions are catalyzed by bacterial enzymes in the intestine. Bottom Section (Diagram): Cholesterol 7-α-hydroxylase 7-α-hydroxycholesterol Several steps Cholic acid Chenodeoxycholic acid Glycine Taurine Glycocholic acid Taurocholic acid Glycochenodeoxycholic acid Taurochenodeoxycholic acid Intestinal bacteria Deoxycholic acid Lithocholic acid Sepithesis of steroid hormones from cholesterol cholesterol is the precursor for the synthesis of all the five classess of steroid hormones a) glucocorttioids (45-Cortisol) by minimalcorticoids / Es- aldosterone) C) progenstine CES-progesterone) d) androgens (Es-testosterons) 2) estrogens (Es-ostrodiol)