University:
Liberty University
Course:
BIOM 500 | Introduction to Biomedical Sciences
Academic year:

2024
Views:

320

Pages:

5
Author:

Sheha A.

Functions of Pancreatic Lipase Lipid digestion: The triglycerides in the intestine digest. A protein secreted by pancreas, colipase, acts as a cofactor for pancreatic lipase. Pancreatic lipase attacks the primary ester linkage in C-4 and C-1 of triglycerides by hydrolyzing ester linkages to producing 2-monoglyceride and then 2 fatty acids are released at each step. An isomerase shifts the ester bond from C-2 to C-1 to convert 2-monoglyceride to 1-monoglyceride which is hydrolyzed by lipase from glycerol and fatty acid. Depending upon the presence of double bond: a) Saturated Fatty Acids All the carbon atoms are joined by a single bond. Each carbon atom carries a hydrogen atom. The general chemical formula is CnH2nO2. They have higher melting points. They are solid at room temperature. Less abundant in living organisms. Occurs in animal fat. E.g.: Stearic acid, palmitic acid. b) Unsaturated Fatty Acids Two adjacent carbon atoms at one or more places lack hydrogen atoms and are linked by a double bond. They have lower melting points. They are liquid at room temperature. More abundant in living organisms. Occurs in plant fats. E.g.: palmitoleic acid, oleic acid. Unsaturated fatty acids are further classified into two types: