University:
Liberty University
Course:
BIOM 500 | Introduction to Biomedical Sciences
Academic year:

2024
Views:

267

Pages:

5
Author:

Sheha A.

Lipid Profile It is a panel of blood tests used to find abnormalities in lipids such as cholesterol and triglycerides in the blood. The results of this test can identify genetic diseases and can approximate risks for cardiovascular disease, certain forms of pancreatitis and other diseases. The Lipid Profile typically includes: Low-density lipoprotein (LDL) High-density lipoprotein (HDL) Total cholesterol Triglycerides A laboratory may calculate very low-density lipoprotein (VLDL) and the LDL to HDL ratio. Typically, the laboratory measures only three quantities: total cholesterol, HDL, and triglycerides. From these three data, LDL may be calculated. (LDL) = (Total Cholesterol) - [HDL] - [Triglycerides] VLDL can be defined as the total cholesterol that is neither HDL nor LDL. With that definition, Friedewald’s equation yields: [VLDL] = [Triglycerides]/5 Ketone Bodies There are 3 ketone bodies present in the body. Primary ketone body: Acetoacetate Secondary ketone bodies: β-hydroxybutyrate Acetone Significance of Ketone Bodies: Ketone bodies being water-soluble are easily transported from the liver to various tissues. Acetoacetate & β-hydroxybutyrate serve as an important source of energy for tissues such as: Brain Skeletal muscle Cardiac muscle etc. The production of ketone bodies and their utilization become more significant during starvation and diabetes mellitus. During starvation, ketone bodies serve as a major fuel source for the brain and other parts of the central nervous system.