University:
McMaster University
Course:
BIOLOGY 4T03 | Molecular and Cellular Neuroscience
Academic year:

2021
Views:

443

Pages:

1
Author:

Sabrina S.

Treatment & prognosis There has been attempts to produce drugs that can reduce withdrawal symptoms or replace the abused substance to treat addiction Methadone has been used as a substitute for neroine with very limited success due to its very weak euphoric effects in addicts. Antabuse has been used with slightly more success to treat alcohol dependency by produang an unpleasant reaction that consists of flushing, headache, nausea, vomiting, dizziness, sweating, pounding heart, blurred vision and weakness when even small armounts of alconor are ingested. Nicotine patones used for smokers A combination of psychotherapy, along with participation in a small group is considered to be the most useful treatment option But even this strategy has a success rate below 50% for most arugs because.... 1. The changes that occur during neuronal tolerances are very long lasting. vulnerability to relapse to chronic alcohol and cocaine abuse appears to be life long 2. The abuse of drugs usually results in the loss of valuable family and personal relationships as well as employment. Drug abuse lowers a Persons standard of living and increases their stress activity latress can mean rotase inter on) 3. cues related to taking the drag (such as drug paraphernalia) are classically conditioned to the dopamine response induced by most arug abuse. Despite prolonged abstinence from a drug, craving and withdrawal symptoms can suddenly reappear if the addict encounters one of these Conditioned stimuli. Cocaine + ethanol = cocaethylene both together produce psychosis at a lower dose than just cocaine by itself Amphetamines dose required to cause release by blocking tramporner 1746 15-HT rolcase), 7.1 (NE release), 25 (DA release) methamphetamine 73615-HT release), 12 (Nt release), 34 (DA release) MDMA lecstasy 74.3.15-HT reacase), (bu (NE release), 2-78 (DA release)