University:
Missouri State University
Course:
BIO 235 | Genetics
Academic year:

2022
Views:

432

Pages:

2
Author:

Derrick Hunt

DNA Mutations Practice Worksheet DIRECTIONS: Transcribe and translate the original DNA sequence. Then, do the same for each mutated DNA sequence. Then, determine the consequence, if any, for each mutation, by circling your choice for each question. You will need a Genetic Code Chart. Original DNA sequence: TAC ACC TTG GCG ACG ACT mRNA transcript: AUG UGG AAC CGC UGC UGA amino acids: Met -Trp - AspArg-Cys - Stop Mutated DNA sequence #1: mRNA transcript: (Circle any changes) TAC ATC TTG GCG ACG ACT AUG UAG AAR CEC UGC UGA amino acids: Met-Stop-Asp-Arg-cys-Stop Type of mutation (Circle one.) How did the mutation affect the amino acid sequence (protein)? (Circle one.) Point Substitution No change 1 amino acid changed Frameshift Insertion or Deletion Premature stop signal No stop signal 1 amino acid added/deleted All the amino acids changed after the point of mutation Mutated DNA sequence #2: TAC GAC CTT GGC GAC GAC T mRNA transcript: (Circle any changes) AUG CUG GAA CCG CUG CUG A amino acids: Met - Leu Glu Pro-Leu-Leu Type of mutation (Circle one.) How did the mutation affect the amino acid sequence (protein)? Point Substitution Frameshift Insertion or Deletion No change 1 amino acid changed Premature stop signal No stop signal 1 amino acid added/deleted All the amino acids changed after the point of mutation (Circle one.) Talk aboul mulation in terms of nitrogen bases AND Amino acids