University:
Northwest College
Course:
VN 210 | Introduction to Pharmacology
Academic year:

2023
Views:

361

Pages:

1
Author:

Yesenia M.

Haloperidol (Haldol) Therapeutic class: conventional antipsychotic; schizophrenia drug Pharmacologic class: d2 dopamine receptor antagonist; nonphenothiazine Actions and uses: for the management of acute and chronic psychotic d/o Can be used to tx pts w tourettes syndrome and children w severe behavior problems such as unprovoked aggressiveness and explosive hyperexcitability. 50 times more potent than chlorpromazine but has equal efficacy in relieving s/s of schizo Beneficial for pts that are uncooperative or unable to take PO meds ADMIN ALERTS: do not dc abruptly Pregnancy category C Onset: 30-35 mins Peak: 2-6hr PO 10-20mins IM Duration: variable A/E : produces less sedation and hypotension than chlorpromazine but the incidence of EPS is HIGH. Older adults most likely to have A/E and are usually prescribed half the adult dose until the a/e of therapy can be determined. BLACK BOX WARNING: older pts w dementia related psychosis are at increased risk for death when taking conventional antipsychotics CONTRAINDICATIONS: giving w nonphenothiazines is not advised. INTERACTIONS: interacts w many drugs Aluminum and mg containing antacids, levodopa, lithium, phenobarbital, phenytoin, rifampin, beta blockers- decrease the effects and absorption of haloperidol. Herbal/food- KAVA may increase effects of Haldol Tx of overdose: severe EPS tx w antiparkinson meds Hypotension- should be tx w IVF, plasma, concentrated albumin or vasopressors.