University:
Northwest College
Course:
VN 210 | Introduction to Pharmacology
Academic year:

2023
Views:

416

Pages:

2
Author:

Yesenia M.

furosemide (gen) - 100p diuretic' MAX: 600mg/day po Dose: 20-80mg in one or divided doses LASIX (trade) Therapeutic class: brug for HF/HIN Pharmacologic class Diuretic (100p diuretic) max: 600mg/day IV: 20-40mg/maxtoonglday ACTION/USES: tx for acute HFb/c removes large amt fluids in short time IV-diuresis th 5 mins * = QUICK RELIEF works by blocking reabsorptions of Nat and Chi in the nephron 1000 Beneficial when cardiac output and renal flow are seventy diminished *check k levels before giving / may need supplements of k + prolonged half-life-uset caution in Infants/neonates *older adults Woses (lover) pregnancy LAT Onset 30-60 min Po Iv 5 min Peak 60-70 min po 10:15-20 min *BLACK BOX WARNING * can lead to profound diuresis Iwater and electrolyte depletion Duration: 6-Bhr PO 2h V contraindications: allergy/ ale: electrolyte Imbalance (HYPOKALEMIA) deliydration, lypotension orthostatic hypotension/syncope OTOTOXICITY (RARE)→Hearing loss Sensitivity to lasix or sulfonamides, anuria(Burine), hepatic coma, severe, fluid/electrolyte depletion. Interactions Hypokalemia can cause dysinymas It taking algoxing aminoglycosides - Can cause nephrotoxicity (ototoxicity. use I corticosteroids can cause more hypokalemia can & hypoglycemic effects of insulin (will ↑ BIS) LOBS: BIS, BUN, Serum amylase, chol, triglycendes, electrolytes Herbal/Food Hawthom (plant) could result in > Hypotensive effects- -Ginseng ran effectiveness of loop diuretics -↑ Na can result in ineffectiveness of diuretics. Tx for overdose replacement of fluids/electrolytes and poss admin of vasopressor (ex: norepinephrine)) to ↑ vasoconstriction cardion (usually given in pts t shock or extremely B/r.) Other loop diuretics loop diuretics can be ototoxic! lasix Bumex torsemide ethacrynic Think loops/Hoops go in your ear) toxiccccc! (↑risk if takent aminoglycosides)