University:
Northwest College
Course:
VN 210 | Introduction to Pharmacology
Academic year:

2023
Views:

265

Pages:

2
Author:

Yesenia M.

hydrochlorothiazicle. (gen) - THIAZIDE DIURETIC abb HCTZ) (Microzide) trade Tor duse 25-100mg/day as tur divided dose Therapeutic class Drug for IITN/edema (mild-med HTN), max 50mg/day *for Hitw Pharmacological class Thiazide diuretic ACTIONS uses most widely Px diuretic for HIV: * Produces 10-20 mmtly reduction in Bl * 100mg/day for capproval to tx ascites, edema, HF, HIN, nephrotic syndrome Facts on Kidney tubule to reabsorption of Nat (DCT) (Chlind heater) More Nat is sent to the urime (Usually 99% is reabsorbed and only!! -water follows sodium = blood vel=bp. sent fourine) Sodium blocked = ait of une produced *yive early in day to AVOID NOCTURIA. Preg CATB onset: 2AR peak: 4 HR A/e: electrolute Imbalance BIS K+/Nat loss. Cardiac abnormalities (Pt need to k Duration: 6-12HK* route Po inlake) -may trigger gout attacks /t hyperuricemig (↑uric acid in blood) contraindications anung allergy/sensitivity to thiazides or sulfonamides preeclampsia ar pregnancy/induced HTN. TX for overdore: Infusions of NS / fluids. Interactions: If taken w/other HIN meds can = synergistic effects/additive. on BIP ( BIP)-Think this med is for HTN→ Will fuck THIN -may reduce eficaey of anticoagulants, sulfonylureas, て the cts. antidiabetic drugs, insulin (BIS) -Questran and colostipol & absorption of this med *↑ risk of nephrotoxicity from NSAIDS * (14L) - k = ↑ digoxin toxicity* - (used for seizures, nerve pain, bipelar Carbamazepine given each others toxicity * Hydrochlorothiazide can↑ LABS: A glucose, chol, bilirubin, triglycondes, CA. ) mg, k, Na. Herbal/Food Ginkgo biloba can produce a Paradoxical ↑ in Blp." (win-k-go-↑) Hawthorne could B/P Hy drochlorothiazide HIN) (Msiaings) High Bunc acid (gout) (hyperмнения) ↓ Jakreancy Hy drochlorothiazide High BP(1x) HIW High BS Iligh unc and goutattook