University:
Northwest College
Course:
VN 210 | Introduction to Pharmacology
Academic year:

2023
Views:

356

Pages:

2
Author:

Yesenia M.

Losartan-geneni Angiotensin lireceptor (Cozaar) trade (think: Locar-xozaar Blocker (ARB) Therapeutic class Drug for hypertension dose: 25-50mg in 1-2 divider doses max 100mg/day). Pharmacological class. angiotensin li receptor blocker (prevars vasoconstrictio promotes vasodilaηση actionsluses upproved for fx Of HTN, reduction of stroke in pis t HTN and ventrcular hypertrophy, and prevention of nephropathy in patients I type 2 pm and Hx of HTN -Has short half life-but metabolizes to an intermediate Tprolonged action making it okay for once-a-day dosing. - actions: Vasodilation, requung blood vol. dit blocking of release of aldosterone by angiotensin II (work on anngiotensin Il - can cause dizziness/fainting-rise slowly after its formed.) *cannot lake if pregnant Pregnancy CAT: D onset: bhes Peak: T.0-1.5hR BLACK BOX WARNING Fetal injury/death may occur when tak my ARBS In pregnancy If detected prignaney. buration: 24 hrs (most common)? ale: Hypoglycemia, dizz mess, 1 Losar , UTI, fatigue, anemia Serious ale angioedema and AKI AKA swelling around Hps, eyes, throat and other body regions can lead to airway Clus coozar ARB Symptomatic hypotension argiotensin reteptor blocker. contraindications pts I sonsitivity/allergy to med. teratogenic effects - for pregnant women dot use aliskiren Aliskiren is Tekturna -Hs another HIN medication) Interactions: drug similar to ACE mhibitor S -NSAID'S reduccahtihypertensive activity and lo CKO - Hyperkalemia when taken potassium spurning diuretics. - Hypotensive effects when taken diuretics and other HIN meds -alkohol = Hypotension -Can↑ Lithium levels toxicity. Lab Tests ↑ BUN, K, creatinine, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) Herbal Food: Grapefruit juice cant antihypertensive achon and ale BIP. Tx of overdose: s/s include diziness / fainting due to Hypotension. TXIV NSTBIP.