University:
Northwest College
Course:
VN 210 | Introduction to Pharmacology
Academic year:

2023
Views:

452

Pages:

2
Author:

Yesenia M.

Nifedepine-gen - Calcium channel blocker (Adalat Procardia XL) trade dose: po (ER) 30-bong QD max (120mg/day) Therapeutic class Drug for HTN and anging cee-nifedipine Pharmacological class: Calcium channel blocker. actionsluses prescribed for HTN and vanant vasospastic anging. -Sometimes for Raynaud's phenomenom (when the spas in it shall arienes Auss so episodes of reiluced blood flow to ind -blocks calcium channels in those myocardial and vascular smooth mu cardiac by ↑ CO in coronary artenes coronary dilation, 02 Usage and in BIP caps • available as IR and ER tabs. (IR Cars IR TABS) -IR approved for HIIN. * Only ER for IN *do admin IR tabs if impending mi is suspected or ithin, 2 weeks following a confirmed mi. -udminister whole-do crush!" (if chewed / crushed divided, whole dose will be delivered at once) Preg Cat: C onser: 30 mins Peak: 6hrs Duration: 24hrs CCC ale constipation cancause constipation * ale: usually minor and rit vasodilation: HA, diziness, peripheral edema, heartburn, nausea, flushing. To avoid rebound HITN, de gradually, all at once. rare: can cause paradoxical↑ in angina pain rit hypotension Or HF. CCBIRH contraindications Prior hypersensitivity lalligy to nifedipine or other CCB'S. Interactions: - Drug additive effects Use T Bela blocker = on blp if taken other HTN meds. Pro HE. (Blockers together. good!!!) -can↑ digoxin = bradycardia and digoxin toxicity (lt) -↑ statins -alcohol potentiates vasodilating action of nifcdepine and could lead to syncope caused by Jin Blp. (alcohol=↓ BIP) alwaryo LABS ↑ alkalne phosphatase, lactase dehydrogenase, ALT, CPK, AST Herball Food Grapefruit juice can enhance absorption. melatonin can ↑ Bly HR [222 (ccc) Interacyst (CCC) (224) Sleeping Ty for overdose: most common s/s hypotension. 1x vasopressors + possible CA infusions. remember it relates back to angina.