University:
Northwest College
Course:
VN 210 | Introduction to Pharmacology
Academic year:

2023
Views:

258

Pages:

2
Author:

Yesenia M.

reteplase-genenc Thrombolythu Retavase-Trade relaplase plas rain blood Therapeutic class Drug for dissolving clors Pharmacological class thrombolytic. actionsluses: acts by cleaving plasminogen to form plasmin. Plasmin degrades fibrin matrix of thrombi -Give ASAP after onset of mi sis. - If given lv bolus acts lin(20 mins 2nd bolys bolys may be to clear Inrombus.) Gren 30 mins after the 155 If needed - after clot dissolved-ty - heparin / other anticoagulant to prevent additional clols * -tx acute/chronic DVT and occluded calhs (off-label) administration alerts - Reconstitute prior to use I divent-swirl tomix-Do not shakel other angs green through same Lv - incompatible & Heparin (don't ever combine in same solution! Pregnancy CAT.C ale abnormal beeting (most senous) Onset: 30 mins Peak 30-90mins Duration: 4811k Maybe prolonged & inj sites and Catheter insert sites pysrhythmias-during myocardial reperfusion contraindications In pts & active bleeding 2 HX of Stroke trecent Sx procedures. canf 110 bleeding. Interactions: drug I ASA, anticoagulants, antiplatelets=additive anti- Coagulant effect and 1 rlo bleeding. Lab Tests: degrades plasminogen in blood samples, ✓ Serum Plasminogen and fibrinogen levels Herbal/Food Ginkgo biloba, ginger, garlic-rlo bleeding Tx overdose specific tx.