University:
Northwest College
Course:
VN 210 | Introduction to Pharmacology
Academic year:

2023
Views:

207

Pages:

2
Author:

Yesenia M.

Propranolol (inderal, Innopran XL) nons Bela Adrenergic antagonist Therapeutic class: Class Il antidysthythmic Pharmacological Class: Beta-adrenergic antagonist Propanolo Low BIS LOW actionsluses: hon selective beta adrenergic antagonist that affects betal receptors in and metas receptors in Pulmonary vascular Smooth muscle. HR myocardial conduction velouty, & DIP. most effective agamst tachycardia caused by excess sympathetic stimulation. -tx's ATN, angina, migraines, prevention of ml. *off label indications & portal HTN and bleeding alt varices. W tachycardial tremors/nevrvousness Ilt thyroid crisisstorn, Panick attacks, PTSD, chronic agitation, agression, involuntary movements of essential tremor. -Avail in tabs ER Caps/N. -Inno pran XL (long acting form designed for bedtime dosing-peaks in am.) *abrupt de poss mit Severe HIIN, ventricular dysrhythmiasst -Tak Ef tabs whok-doschish. HR <60 notify MD. Pregnancy CAT:C onset: po 30-60min peak: 1-dHp Duration: IR U-12HRS ER GHK ER 24-27 HRS ale: Patique, hypotension, bradycardia (monitor PIS T HF for HR) diminished libido, impotence -cause BIS (may mask sls of & BS as the adrenergic "fight or flight" response to hypoglycemia is blocked. -PtS I CKb-may accumulate to toxic levels - dysrhythmias BLACK BOX WARNING-abrupt dll can cause worsening sis of Ischemic disease. gradually reduce over 1-2 weeks. resume if sis angina appear. contraindications: pts & cardiogenic shock. Sinus brady, 7/stdegree Oblak, HP&In Pts Copplasthmaldit effects on b₂ receptors) Interactions (drag): T other beta adrenergic antagonists = additive bradycardia /hypotensioy TCCB/S = additive bradycardia Ido give thin 2 weeks of maol-gerere brady and VBP. antgads = slow absorption | reduce therapeutic effects. beta adrenergic agonists = antagonized actions of propanolol. False(1) Labs of vrinary Catecholamines Herbal Food: 7X overdose: Aypotension by vasopressors brady-txt atropine or Isoproterevol inglucagon- -to reverse cardiac depression by beta-adrenerg Antagonist overdose Genhances myocardial contractrlito HVz and im Iproves no C