Atorvastatin Reference Materials

University:
Northwest College
Course:
VN 210 | Introduction to Pharmacology
Academic year:

2023
Views:

312

Pages:

2
Author:

Yesenia M.

ATORVASTATINSENG STATINS" Upitor-Brand Trade Therapeutic class Antihyperlipidemio Pharmacologic class HMG-CoA reductase inhibitor/STATN Action/uses: Hyperlipidemia to reduce mi/stroke to prevent cardiovascular disease in at risk pts t diabetes/smuking/HTN HX of family disease. STATINS INHIBIT HMG COA REDUCTASE CHOL LDL (Results in 2 wks) complemented diet excersice Jow cat fat's program. cholesterol Herbal Food AVDID GRAPEFRUIT* JUICE (prevents metabolism) RED Yeast Rice-Contains natural Statins toxic levels cant effects of atorvastatin. -Statins can synthesis of coenzyme Q10 (COGID) take supplements Dose: 10-20mg po dally. CUQIO is essential to produce ATP. URlo Heartattack Sip MI, HIN, migraines, Capable of producing 50/ drop in LDL Parkinson's ↑ Immune Prevents blood vesal damage SIP SX Route po food (to & Gl discomfort) Time: Anytime. Pregnancy OAT.X *tx for overdose ONSET:2 VIKS PEAK-1-2 HR DURATION UNKNOWIN AJE: Hepatotoxicity / Rhabdomyolysis SIE GI complants/cramping diarrhea/constipation CONTRAINDICATIONS: disrage ↑ serum transaminases, prior reaction/Hypersensitivity to ding. LABS cenim transaminase - and creatinine. DRUG INTERACTIONS: Interacts t A 20le antifungals A Hiv protease inhibilors thabdo and Telaprevir Myopathy [ Can levels of digoxin & oral contraceptives. Erythromycin ↑ Atorvastatin levels 40% macrolide AB Xach rhabdo risk] - Cyclosporine/Niacin AVOID ETHANOL