PRACTICUM 5: MANUFACTURING TABLET PREPARATIONS WET GRANULATION METHOD: CHEWABLE TABLETS OBJECTIVE Students can find out the process of making tablets using wet granulation. COMPLETE FORMULA R/Al(OH)3 300 mg PVP 5% Mannitol qs Aspartame 5 mg Talc: Magnesium stearate (9:1) 10 mg Tablet weight 450mg WEIGHING 1. Do a study to review the formula above. 2. Weighing is carried out to make 300 tablets. PROCESSING 1. Weigh Alumina, PVP and Mannitol. Mix in a container while stirring until homogeneous. 2. Spray the mixture with distilled water while stirring until granules form. Granules were sifted with sieve no. 12. 3. Spread the sifted granules into a flat container and dry in the oven. 4. Add Aspartame, Talc and Magnesium stearate to the dry granules. Stir until homogeneous. 5. Perform internal phase granule evaluation. 6. Mold the granule mixture until it completely forms a tablet. 7. Evaluate the tablet in the next practicum. PRACTICUM 6: MANUFACTURING TABLET PREPARATIONS DIRECT COMMISSION METHOD OBJECTIVE Students can find out the process of making tablets using the Direct Compression method. COMPLETE FORMULA R/ VITAMIN C 100 mg Avicell pH 102 qs Amylum 5% Talcum 2% Mg Stearate 1% Tablet weight 350mg WEIGHING 1.Do a study review of the formula above. 2.Weighing was carried out to make 300 tablets. MAKING PROCESS 1.Weigh the substances in the formula. Mix in a container while stirring until homogeneous. 2.The mixture was sieved with sieve no. 12. 3.Perform all stages of granule evaluation. 4.Mold the granule mixture until it completely forms a tablet. 5.Evaluate the tablet. MODULE 7: PRACTICUM ON PHARMACEUTICAL TECHNOLOGY SOLIDA PREPARATIONSASPECTS OF GOOD MEDICINE MANUFACTURING I. PURPOSE To deepen and understand aspects of CPOB II. SCOPE Conduct studies on each aspect of CPOB III. SPECIAL ATTENTION The assessment was carried out in the pharmaceutical technology laboratory IV. EQUIPMENT Handbook on Good Medicine Manufacturing Methods V. PREPARATION FOR TESTING 1. An assessment is carried out to find out why and the relationship of each aspect to the quality of the solid dosage form produced. 2. Preparing a paper on the results of the study carried out.