MINUTE ESSAY 4 Equine Hyperlipidemia Foregut vs Hindgut Energy Metabolism -Poregut stomach, small intestine •stomach enzymatic digestion, breakdown of carbs #proteins -small intestine nutrient absorphon -nutrient breakdown yields readily available energy, in the form of glucose, simple sugars Permentation produces VFA's, can be absorbed # Uhlized directly for energy Maintenance of Normal Blood Glucose During Energy Balance - energy balance: horses consume fewer calories, deficit in available energy • insufficient feed intake, Tenergy demands (lactation, exertising) health conditions - -gluconeogenesis -gNcogenoNSIS -fatty aud oxidation How Insulin Resistance Polentiates Lipolysis -Insulin: hormone crucial for regulating glucose & lipid metabolism •suppresses breakdown of stored fats, promotes storage of excess energy as fats in adipose tissue -insulin resistance •cells less responsive to insulin, impaired signaling, inhibitory effect on lipolysis is diminished •adipose tissue starts releasing more Free FA into bloodstream -increased lipolysIS: • elevated levels of circulating free FA Calculating RER Resting Energy Requirement -RER=70xBW-15 kcal/day 10x (250 kg) 75 kcal/day = 4,401 kcal/day Problems with AppNing to Hospitalized Patient -resting energy expenditure is much lover DER×2=MER RER 15=MER Diet to correct Energy Balance Restore Energy Balance -sufficient energy supply stimulate insulin secretion, switch off lipolysis -HIGH CARB, LOW FAT Administration of Synthetic Throxine Benefits hyperlipidemic patients -thyroxine thyroid increase metabolic rate free FA in arculation will be taken up into tissues & Whired for energy Mare w/ Hyperlipidemia X -hyperlipidemia: not getting enough energy, experiencing stress •not getting enough energy to support healthy weight or lactation -hindgut cecum, large intestina •fibrous materials & carlbs that escaped paregut more to the hindgut produce VEAS, can •microbial fermentation be absorbed & uhlined for energy after SI, not as energy efficient

Exam 3 Minute Essay 4

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