University:
Eastern Kentucky University
Course:
BIO 273 | Clinical Microbiology
Academic year:

2022
Views:

248

Pages:

1
Author:

sonalhava9qv

Helicobacter Pylori (-) Features: 1. Oxidase (+) 2. Curved gram negative rod 3. Urease (+) a. Splits urea into NH3 and CO2 i. NH3 neutralizes the acidity of stomach Lab Diagnosis: 1. Urea breath test a. Patient swallows urea labeled with radioactive carbon b. CO2 produced (if urease positive organism is present in stomach) has radioactive carbon in it which can be detected in breath 2. Biopsy during endoscopy a. The biopsy taken is directly checked by rapid urease test Diseases: 1. Ulcers a. Duodenal ulcers most common (95%) 2. Increases the risk of adenocarcinoma of stomach 3. May also cause lymphoma of mucous associated lymphoid tissue (MALT) a. Also called maltoma Treatment: 1. Triple therapy regimen a. Proton Pump Inhibitors b. Macrolides (clarithromycin) c. Amoxicillin