University:
University of Wolverhampton
Course:
4PY019 | Pharmacy
Academic year:

2023
Views:

402

Pages:

2
Author:

Carisma

1. What is malaria and how is it caused?: Black water fever and caused by protozoan plasmodium falciparum and mosquito bites 2. Treatment for malaria: Chloroquine Quinine 3. What is plague and what causes it?: Infection spreads to lympathic system causing buboes. Caused by yesrinia pestis transmitted by infected rat bites. 4. Treatment for the plague: Antibiotics (gentamicin or streptomycin ) 5. What is the transient and chronic appearance of bacterial growth known as?: Bacteraemia and septicaemia 6. What causes anthrax?: inhaling spores of Bacillus anthracis. Eschars and malignant pustules appear 7. Treament for anthrax?: Antibiotics- Ciprofloxacin + doxycycline 8. What causes leptospirosis?: Leptospira interrogans through contaminated food or drink. Causes fever followed by hepatitis and hemorrhages of liver and kidney. 9. Treatment for leptospirosis: Antibiotic- doxycycline or penicillin 10. What causes herpes I?: Herpes simplex virus lies dormant in dorsal root ganglion. Cold sores appear 11. What causes genital herpes?: Herpes Simplex Virus -2 12. What causes chicken pox and shingles?: varicella zoster virus. Shingles occurs when virus lies dormant in dorsal root ganglion to be rectivated. 13. Treatment for chicken pox and shingles: Acyclovir (anti-viral drug) Anti-inflammatory drugs (ibuprofen) 14. What causes rabies?: Rhabdovirus from bite of rabid animal. Causes agitation, hydrophobia, hallucinations and salivation. 15. What two toxin types do microbes possess?: Endotoxins- structural components of cell wall causing disease e.g LPS (gram -ve), lipotechoic acids (gram +ve), zymozan. Exo toxins - secreted from cell to cause effects. 16. what is sterilisation?: Complete destruction or elimination of all viable microorganisms. 17. Which antibiotics target the ribosomes?: Tetracyclines (BS) + gentamycin (BC) (30s) Erythromycin (BS) + Chloramphenicol (BS)(50s) 18. Which antibiotic prevents transcription?: Rifampicin (BC) 19. Which antibiotic affect folate metabolism?: Sulphonamides (BS)+ trimethoprim (BS) 20. Which antibiotics affect cell walls?: B-lactams (BC)(inhibit transpepdidase) Vancomycin (BC)(Glycopeptide antibiotic) 1/2 21. Which antibiotic affect DNA replication?: Nalidixic acid (BC) (inhibit DNA gyrase- prevents super coiling) Ciprofloxacin (BS) 22. What is the decimal reduction time (D)?: Time taken or the radiation dose requierd to achieve 90% reduction in viable cells. 23. What is the Z-value?: the temperature required to reduce the D-value of an organism by 90% 2/2