Synthesis: CfP1 | University of Wolverhampton - Edubirdie

University:
University of Wolverhampton
Course:
4PY019 | Pharmacy
Academic year:

2024
Views:

34

Pages:

1
Author:

Sara

1. risk assess the experiment (e.g. what are the hazards?) 2. pick the correct equipment 3. calculate the amount of reagents needed what are the 8 steps to practical lab syn4. check the reaction is complete by TLC thesis? 5. purification 6. calculate a % yield 7. characterise using analytical techniques 8. check purity mols = mass/Mr density = mass/volume molarity = mols/volume what class of drug is dofetilide? Class III anti-arrythmic agent what ion does dofetilide have an effect on? affects K+ efflux out of the heart cells what is dofetilide used for? treatment of atrial fibrillation and flutter what class of drug is cetirizine? anti-histamine what receptor does cetirizine bind to? histamine H1 receptor what class of drug is landiolol? anti-arrhythmic agent what receptor is landiolol selective for? ²1-selective (cardi-selective) what class of drug is glipizide? sulfonylurea, used in the treatment of diabetes how does glipizide work? partially blocks K+ channel in the ²cells of the pancreas, encouraging release of insulin what class of drug is imatinib? chemotherapeutic agent, brand name = Gleevec what is imatinib commonly used to treat? chronic myelogenous leukaemia acute lymphatic leukaemia cancers what does imatinib inhibit? TK (tyrosine kinase) 1/1

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