University:
University of Wolverhampton
Course:
4PY019 | Pharmacy
Academic year:

2024
Views:

426

Pages:

3
Author:

Sara

1. Where are the kidneys located? between the peritoneum + posterior muscular wall of the abdomen 2. Where are 80% of the in the cortex nephrons found? 3. Where are 20% of nephrons found? medulla (juxtamedullary nephrons) 4. What does ultrafiltrate mean? fluid that a nephron works one that becomes urine at the end of a collecting duct 5. Where do collecting the calyxes + then the renal pelvis ducts drain towards? 6. What is the glomeru- primary filtration lar corpuscle the site of? 7. Why is lots of mienergy is needed to reabsorb substances against tochondria found in gradient the cells that form the PCT? 8. What is Furosemide? a diuretic drug 9. What is a diuretic? increases volume of urine 10. Where does in the ascending part of the loop of Henle by blocking Furosemide exert its salt reabsorption action? 11. What determines the reabsorption + secretion amount of urine that is formed? 12. Where is glucose re- PCT absorbed? 13. 1/3 What stops filtration the pores of the fenestrated endothelium are not big of blood cells through enough the glomerulus? 14. What is thiazide? a diuretic 15. What is the mechanism of Thiazides? inhibition of salt reabsorption in the DCT 16. What is the drug Amiloride? a diuretic 17. What is the mechanism of the drug Amiloride? inhibits epithelial sodium channel in the collecting duct 18. When is water reabsorbed in the collecting tube of the nephron? only when stimulated by anti-diuretic hormones (ADH) 19. What is renin? an enzyme in the kidney 20. What does renin do? converts angiotensinogen to angiotensin I 21. What does the anconverts angiotensin I to angiotensin II giotensin converting enzyme do? 22. What type of fat cov- perirenal fat ers the kidneys? 23. When in renin released? 1) drop in BP in afferent arteriole ( detected by baroreceptors) 2) Na+ levels drop 3) sympathetic innervation activates juxtaglomerular cells 24. What is angiotensin II? a generalised vasoconstrictor that cause smooth muscle cells to contract 2/3 25. What does angiotensin II stimulate? release of aldosterone from the adrenal glands in the cortex 26. What does vasopressin do? it's an ADH that increases water reabsorption 27. What does anincreased thirst sensation giotensin in the hypothalamus cause? 3/3