IDM Competitive Antagonist - Edubirdie

University:
University of Wolverhampton
Course:
4PY019 | Pharmacy
Academic year:

2024
Views:

99

Pages:

1
Author:

Sara

1. competitive antagonist: - bind selectively to receptors + block receptors therefore they interfere with the agonist-receptor interaction 2. Given that this drug has a pKa of 4.8, would this drug be absorbed in the stomach? Briefly explain you answer Henderson-Hasselbalch equation (i.e. HA Ì H+ + A-) This drug is weakly acidic, in acidic environments (pH 1-2 in the stomach), the equation will shift to the left (the unionised form) and this is more membrane permeable (i.e. "like-dissolves like"). Therefore it will be absorbed by the stomach 3. if lh increase does - an increase in LH can lead to an increase in progesprogesterone in- terone levels. LH surge triggers ovulation crease: - which results in the formation of the corpus luteum. - The corpus luteum then secretes progesterone, which helps maintain the uterine lining for a potential pregnancy 4. FSH stimulates follicle growth, leading to estrogen production. Estrogen thickens the uterine lining. LH surge triggers ovulation, releasing the egg 5. morphine primary metabolite 1/1

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