University:
University of Wolverhampton
Course:
4PY019 | Pharmacy
Academic year:

2024
Views:

317

Pages:

3
Author:

Sara

1. What is made API during primary manufacturing? 2. What is secwhen the active ingredient is mixed with other agents to ondary manufac- create the physical form required for the delivery of the turing? drug 3. Describe oral ad- - delivery via the gastrointestinal tract ministration: - pros = non invasive, convenient - not approp for unconscious patients, time needed for absorption + distribution 4. Describe oral dosage forms: - oral powders = bulk powders (multi dose prep of solids, loose, dry particles) - oral powders = divided powders (single dose presentations like on a small sachet) 5. Describe granules: - agglomerates of powder mixes usually of drug + excipients - some granules placed on tongue + swallowed with water + others intended to be dissolved in water before taking - effervescent granules evolve CO2 when added to water 6. Describe tablets: - solid dosage forms consisting of active ingredients + suitable pharmaceutical excipients - pros = accurate, compact - cons = slow dissolution 7. Describe 1 type of excipients for compressed tablets: - filler (/ diluent) - increases tablet size - not necessary if dose is high - lactose is a common filler 1/3 8. Another type of excipient: - binder - such as starch paste - usually added to promote granulation = to ensure free flowing properties of particles - can provide cohesive compacts 9. Another type of excipient: - disintegrants - starch for example - helps the tablets to dissolve into small fragments 10. Another type of excipient: - glidant - improves flowability of the tablet granules/powder by reducing friction between particles - prevent lump formation - commonly used glidant = colloidal silica 11. Another excipient: - anti adherent = stops powder from sticking to the equipment as tablet being made - lubricant = ensures the tablet has a smooth surface 12. Describe what an - a liquid oral prep which contains a potent/unpleasant elixir is: tasting drugs - usually clear formulation with high proportion of sweetening agent 13. What is linctus? - a liquid oral prep used for a demulcent = forms a soothing film over a mucous membrane + relieves mild pain + inflammation 14. Evaluate the pros - pros = drug doesn't pass through intestinal tract + cons of IV ad- - fast action ministration: - cons = invasive - can introduce bacteria into the system 15. Intramuscular in- - pros = fast but not as fast as IV administration jection pros + - can be formulated for extended release cons? - cons = invasive 2/3 - can cause bruising - not suitable for patients with decrease muscle mass 16. Pros + cons - pros = doesn't pass through intestinal tract of subcutaneous - patients can be taught to self administer administration: - cons = invasive - may introduce bacteria into the system 17. What are subeffective for vaccines + insulin cutaneous injections useful for? 3/3