Chemistry / PCC1 Science Quiz | University of Wolverhampton - Edubirdie

University:
University of Wolverhampton
Course:
4PY019 | Pharmacy
Academic year:

2024
Views:

411

Pages:

2
Author:

Sara

1. Which of the follow- Adenosine ing is NOT classified as a secondary metabolite-based natural product from a medicinal chemistry perspective? 2. Which of the following Amides is NOT a class of natural product? 3. Which one of the The molecule can be protonated and therefore infollowing statements volved in ionic interaction with a biological receptor is FALSE, when you consider the potential of Stiripentol, to be involved in intermolecular/intramolecular bonding interactions? 4. Which one of the following statements is FALSE, when you consider the potential of Stiripentol, to be involved in intermolecular/intramolecular bonding interactions? Explain answer - protonation typically involves the addition of a proton (H+) to a molecule, leading to a formation of a positively charged species, not necessarily ionic interactions with biological receptors 5. How can a molecule act as a hydrogen bond donor + acceptor? - if it contains functional groups that have hydrogen atoms bonded to electronegative atoms like oxygen/nitrogen - it has hydrogen atoms bonded to electronegative atoms for hydrogen bond donor 1/2 - if the electronegative atom like oxygen/nitrogen with lone pairs of electrons, these lone pairs form H bonds that are covalently bonded to other electronegative atoms (hydrogen bond acceptor) 6. Which of the following Drug metabolism must occur to avoid toxicity statement is INCORRECT when considering drug metabolism? 7. The incorrect state- Drug metabolism must occur to avoid toxicity ment when considering drug metabolism - drug metabolism can sometimes lead to the formation of toxic metabolites / reduce toxicity 8. Which amino acid Prolin does NOT contain a primary amine? (contain amino group NH2) 2/2

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