CVS Basic Info | Western Sydney University - Edubirdie

University:
Western Sydney University
Course:
MEDI 2003 | Clinical Sciences 2
Academic year:

2024
Views:

451

Pages:

3
Author:

Mariam A. A.

CVS Small sample of the chorionic villi of the placenta Sample collected via needle and is ultrasound guided Done between 11 and 13 weeks Basic Info After ~14 weeks, the placenta becomes more vascular and fibrotic, making sampling harder and increasing bleeding risk. Two types: Transabdominal – most common Transcervical – less common Women who are 37 and over Women with suggestive features on first trimester screening, maternal serum screening or ultrasound Women who already had a child with down syndrome or CF Women known to have a hereditary condition that may get passes to the foetus Indications Can detect: Chromosomal abnormalities Single gene disorders e.g. sickle cell, thalassemia Mosaicism Sex determination Ultrasound to check for GA, placenta position, number of babies. Also check HRNeed to have a moderately full bladder (to help elevate the uterus)Abdomen cleaned with a septic solution Local anaesthetic (more likely to be used her)Slender needle inserted under U/S guidance until reaches placenta Finer needle inserted -> draws very small fragments of placenta tissue Procedure Most experience discomfort in procedure but not severe 1 in 200 or 0.5% risk of miscarriage Weigh against risk of down syndrome Vaginal bleed In 10% of cases More common in transcervical approach Complications Infection Rare Amniotic fluid leakage Rare Like another test may fail due to: Inadequate sample Lab cannot produce a result

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