University:
Western Sydney University
Course:
MEDI 2003 | Clinical Sciences 2
Academic year:

2024
Views:

214

Pages:

1
Author:

Mariam A. A.

Enterobacteriaceae Many strains Some normal intestinal microbiota Some opportunistic, some have developed virulence Transmission Person-to-person Contaminated food/H₂O Dislocation from intestinal tract Pathogenic E. coli Enterotoxigenic → secretion of fluid loss Enteroinvasive → invade cells → inflammation → colitis Enteropathogenic → wasting form of infantile diarrhea Enterohemorrhagic → hemorrhagic syndrome & kidney disease Tx Antibiotics 3rd generation cephalosporins, quinolones, doxycycline, aminoglycosides Sulfamethoxazole/trimethoprim Anti-diarrheal meds Klebsiella Pneumoniae Normal flora of resp. tract Gram-negative bacilli Make large capsule Opportunistic infections Nosocomial pneumonia, meningitis, bacteremia, UTIs, wound infections Salmonella Well-developed virulence factors Not part of normal flora Salmonella enterica serotypes 1, 2, 4, 5, 12 1, 4, 5 → typhoid fever 2, 3 → extraintestinal symptoms 6, 7, 8 → bloody diarrhea Tx IV fluids with electrolyte replacement Ciprofloxacin, ceftriaxone If very severe, bactrim