University:
Western Sydney University
Course:
MEDI 2003 | Clinical Sciences 2
Academic year:

2024
Views:

111

Pages:

1
Author:

Mariam A. A.

Local Anesthetics 2 classes: Esters, Amides Esters: rapidly absorbed into bloodstream, more likely to elicit allergic reactions Amides: more likely to be tolerated but don't cross BBB Used for minor procedures When there's a need for localized anesthesia For procedures like dental extractions or getting a polyp from your nose Effect on nerve: Blocks Na+ channels AP decreases Pain perceptions by the brain To counteract this: Vasoconstrictors given (e.g., epinephrine) Longer doses can inhibit: Restlessness, anxiety, & seizures All neurons Respiratory depression Role of AP on myocytes in the heart Bradycardia Vasodilation Hypotension Methods of Administration: Topical: skin, mucosa Nerve block: injected near a major nerve Infiltrated into tissues or around nerve space or subarachnoid space Used for orthopedic procedures like joint replacement, C-sections, & pain management in child delivery Side Effects: Restlessness, anxiety, & seizures All neurons Respiratory depression Role of AP on myocytes in the heart Bradycardia Vasodilation Hypotension