Sex-Linkage or X-Linked Inheritance - Edubirdie

University:
Western Sydney University
Course:
MEDI 2003 | Clinical Sciences 2
Academic year:

2024
Views:

75

Pages:

2
Author:

Mariam A. A.

Sex-Linkage or X-Linked Inheritance Sex linkage is the phenotypic expression of an allele that is dependent on the gender of the individual and is directly tied to the sex chromosomes. ✓ Sex-linked traits are characteristics whereby the alleles responsible for them are only located on the X chromosome. This means that there is no allele responsible for the sex-linked trait on the Y chromosome. Only male gametes have Y sex chromosomes. ✓ The alleles that are responsible for expression sex-linked traits are recessive. ✓ This means that males only require one of the recessive allele for the sex-linked trait to be expressed as there is no second allele on the Y chromosome to allow the overriding of the recessive allele on the X chromosome in males. ✓ Females, however, have two X sex chromosomes. In each chromosome, there is one allele that codes for the sex-linked trait (for example having colourblindness or normal colour vision). If one of the female’s X chromosome contains the recessive allele responsible for the colour blindness and the other X chromosome contains the dominant allele (normal colour vision), the female will not be colour-blind. ✓ This is important because the offspring’s gender (more specifically offsprings’ sex chromosomes) plays a role in determining whether or not the offspring will express the sexlinked trait such as colour-blindness. Pedigrees A pedigree chart is a diagram that shows the occurrence and appearance of phenotypes of a particular gene or organism and its ancestors from one generation to the next. How to read pedigree charts Whoever is more to the left is older. And whoever is more at the top is older.

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