Autosomal Inheritance Study Resources | Western Sydney University - Edubirdie

University:
Western Sydney University
Course:
MEDI 2003 | Clinical Sciences 2
Academic year:

2024
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419

Pages:

3
Author:

Mariam A. A.

Autosomal inheritance ✓ In humans, there are two alleles for a given gene where the alleles help determine the trait of organism. ✓ Autosomal inheritance is the inheritance pattern occurring similarly in males and females because the alleles responsible are carried on autosomal. Mendel’s work is responsible for giving us understanding of the patterns of autosomal inheritance. His experiments on cross breading lines of pea plants are true breeding. He documents traits in the offspring (called the F1 generation) and then crossed the F1 generation together to produce the F2 generation. The experiments are called monohybrid crosses because they traced the inheritance of one trait only (hence, mono) and the patterns had alternative forms of the trait (hence hybrid). True breading: Forms of organisms that possess traits that are always carried on to their offspring; this means that offspring show no variation for that trait. F1 generation: The first generation of offspring produced by a set of parents. The 'F' in F1 stands for 'filial.' So, in short, F1 means 'first filial generation’. In other words, it is the direct offspring of a controlled cross. F2 generation: F2 generation is the result of a cross between two F1 individuals (from F1 generation) Monohybrid Cross: A cross between two pure-breeding parents that differ in the alleles they carry for a particular gene. For example, one parent has the allele for the white petal trait and the parent has the allele for the red petal trait. (different traits crossing over) Example Each parent will have two alleles for its eye colour gene. Suppose that: ✓ The mother has an allele that codes for blue eye colour and an allele that codes for black eye colour. ✓ The father has both alleles that code for black eye colour. ✓ Let’s also suppose that the allele that codes for black eye colour is denoted by ‘B’ and the blue eye colour is denoted by ‘b’.

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